HitPredict

Interactor 1: RHBT1 (O94844)
Rho-related BTB domain-containing protein 1
Gene: RHOBTB1

Interactor 2: CSN2 (P61201)
COP9 signalosome complex subunit 2 (SGN2) (Signalosome subunit 2) (Alien homolog) (JAB1-containing signalosome subunit 2) (Thyroid receptor-interacting protein 15) (TR-interacting protein 15) (TRIP-15)
Gene: COPS2

Species: Homo sapiens

Source: intact

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.54	0.60	0.571

Property	Details
Experiments	31871319, unassigned3799
Identification Methods	affinity chromatography technology, anti tag coimmunoprecipitation
Interaction Type	physical association, association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0007165 - signal transduction
Homologous interactions	14

Homologous interactions

Color coding for hit scores

	1 696 Hs			1 443
+	Hs
		958708 RHBT2_HUMAN (1-690): 4.26e-168: 501: 67.94		CSN2_HUMAN (1-443): 3.16e-127: 377: 100.00
+	Hs
		318751 RHBT1_HUMAN (1-696): 0: 538: 100.00		CSN1_HUMAN (17-443): 7.06e-80: 257: 15.02
+	Hs
		318868 RHBT1_HUMAN (1-696): 0: 538: 100.00		CSN4_HUMAN (54-440): 8.18e-74: 238: 16.25
+	Hs
		128313 RHBT2_HUMAN (1-690): 4.26e-168: 501: 67.94		PSD12_HUMAN (39-440): 8.73e-83: 263: 12.80
+	Hs
		1094411 RHBT2_HUMAN (1-690): 4.26e-168: 501: 67.94		CSN1_HUMAN (17-443): 7.06e-80: 257: 15.02
+	Hs
		1413193 RHBT2_HUMAN (1-690): 4.26e-168: 501: 67.94		CSN4_HUMAN (54-440): 8.18e-74: 238: 16.25
+	Hs
		958725 IBTK_HUMAN (208-637): 1.88e-71: 255: 14.77		CSN2_HUMAN (1-443): 3.16e-127: 377: 100.00
+	Hs
		127917 CDC42_HUMAN (12-218): 1.56e-89: 279: 37.14		PSD11_HUMAN (35-442): 5.46e-89: 278: 22.43
+	Hs
		128193 CDC42_HUMAN (12-218): 1.56e-89: 279: 37.14		PSD12_HUMAN (39-440): 8.73e-83: 263: 12.80
+	Hs
		127834 SPOP_HUMAN (300-648): 4.67e-73: 242: 15.32		PSD11_HUMAN (35-442): 5.46e-89: 278: 22.43
+	Hs
		227533 SPOP_HUMAN (300-648): 4.67e-73: 242: 15.32		CSN1_HUMAN (17-443): 7.06e-80: 257: 15.02
+	Hs
		1413209 IBTK_HUMAN (208-637): 1.88e-71: 255: 14.77		CSN4_HUMAN (54-440): 8.18e-74: 238: 16.25
+	Hs
		1015403 RHOG_HUMAN (12-210): 1.95e-69: 226: 36.63		CSN1_HUMAN (17-443): 7.06e-80: 257: 15.02
+	Hs
		1015726 RHOG_HUMAN (12-210): 1.95e-69: 226: 36.63		CSN4_HUMAN (54-440): 8.18e-74: 238: 16.25