HitPredict

Interactor 1: CDK14 (O94921)
Cyclin-dependent kinase 14 (EC 2.7.11.22) (Cell division protein kinase 14) (Serine/threonine-protein kinase PFTAIRE-1) (hPFTAIRE1)
Gene: CDK14

Interactor 2: 1433T (P27348)
14-3-3 protein theta (14-3-3 protein T-cell) (14-3-3 protein tau) (Protein HS1)
Gene: YWHAQ

Species: Homo sapiens

Source: intact

Category: Small-scale

Confidence: High

Method score	Annotation score	Interaction score
0.75	0.60	0.674

Property	Details
Experiments	16775625, 36931259, unassigned3799
Identification Methods	two hybrid, affinity chromatography technology, anti tag coimmunoprecipitation
Interaction Type	direct interaction, physical association, association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0005634 - nucleus GO:0005737 - cytoplasm GO:0005829 - cytosol
Homologous interactions	20

Homologous interactions (Top 20)

Color coding for hit scores

	1 469 Hs			1 245
+	Hs
		322097 CDK14_HUMAN (1-469): 2.13e-162: 469: 100.00		1433E_HUMAN (2-243): 1.32e-144: 406: 63.53
+	Hs
		322098 CDK14_HUMAN (1-469): 2.13e-162: 469: 100.00		1433Z_HUMAN (1-245): 1.76e-141: 397: 79.59
+	Hs
		322093 CDK14_HUMAN (1-469): 2.13e-162: 469: 100.00		1433B_HUMAN (1-242): 5.04e-139: 391: 81.82
+	Hs
		667720 CDK2_HUMAN (132-429): 4.68e-141: 408: 50.33		1433E_HUMAN (2-243): 1.32e-144: 406: 63.53
+	Hs
		667543 CDK2_HUMAN (132-429): 4.68e-141: 408: 50.33		1433T_HUMAN (1-245): 9.51e-142: 398: 100.00
+	Hs
		667748 CDK2_HUMAN (132-429): 4.68e-141: 408: 50.33		1433Z_HUMAN (1-245): 1.76e-141: 397: 79.59
+	Hs
		971409 CDK3_HUMAN (132-437): 2.13e-137: 398: 51.30		1433E_HUMAN (2-243): 1.32e-144: 406: 63.53
+	Dm
		120639 M9PE01_DROME (37-457): 3.11e-134: 399: 53.79		1433E_DROME (2-242): 6.8e-143: 401: 65.02
+	Dm
		1019865 Q7KM03_DROME (37-452): 4.48e-134: 398: 54.19		1433E_DROME (2-242): 6.8e-143: 401: 65.02
+	Hs
		690906 CDK3_HUMAN (132-437): 2.13e-137: 398: 51.30		1433T_HUMAN (1-245): 9.51e-142: 398: 100.00
+	Hs
		729749 CDK3_HUMAN (132-437): 2.13e-137: 398: 51.30		1433B_HUMAN (1-242): 5.04e-139: 391: 81.82
+	Hs
		690934 CDK18_HUMAN (3-466): 1.05e-131: 390: 45.69		1433T_HUMAN (1-245): 9.51e-142: 398: 100.00
+	Hs
		729770 CDK18_HUMAN (3-466): 1.05e-131: 390: 45.69		1433B_HUMAN (1-242): 5.04e-139: 391: 81.82
+	Hs
		322101 CDK14_HUMAN (1-469): 2.13e-162: 469: 100.00		1433F_HUMAN (2-242): 7.19e-106: 307: 71.43
+	Hs
		322096 CDK14_HUMAN (1-469): 2.13e-162: 469: 100.00		1433G_HUMAN (1-242): 5.51e-105: 305: 70.33
+	Hs
		667799 CDK2_HUMAN (132-429): 4.68e-141: 408: 50.33		1433F_HUMAN (2-242): 7.19e-106: 307: 71.43
+	Hs
		667710 CDK2_HUMAN (132-429): 4.68e-141: 408: 50.33		1433G_HUMAN (1-242): 5.51e-105: 305: 70.33
+	Hs
		730512 CDK3_HUMAN (132-437): 2.13e-137: 398: 51.30		1433S_HUMAN (1-236): 9.9e-108: 312: 71.85
+	Hs
		1025253 CDK3_HUMAN (132-437): 2.13e-137: 398: 51.30		1433F_HUMAN (2-242): 7.19e-106: 307: 71.43
+	Hs
		730533 CDK18_HUMAN (3-466): 1.05e-131: 390: 45.69		1433S_HUMAN (1-236): 9.9e-108: 312: 71.85