HitPredict

Interactor 1: WDR47 (O94967)
WD repeat-containing protein 47 (Neuronal enriched MAP-interacting protein) (Nemitin)
Gene: WDR47

Interactor 2: TAU (P10636)
Microtubule-associated protein tau (Neurofibrillary tangle protein) (Paired helical filament-tau) (PHF-tau)
Gene: MAPT

Species: Homo sapiens

Source: intact

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.47	0.60	0.536

Property	Details
Experiments	35063084
Identification Methods	proximity labelling technology, anti tag coimmunoprecipitation
Interaction Type	physical association, association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0000226 - microtubule cytoskeleton organization GO:0005737 - cytoplasm GO:0005874 - microtubule GO:0030425 - dendrite GO:0030426 - growth cone and 1 others more... GO:0043025 - neuronal cell body
Homologous interactions	18

Homologous interactions

Color coding for hit scores

	1 919 Hs			1 758
+	Hs
		529555 GBB2_HUMAN (563-916): 2.61e-78: 260: 20.17		TAU_HUMAN (1-758): 6.41e-90: 300: 100.00
+	Hs
		529281 LIS1_HUMAN (838-919): 7.9e-20: 94.8: 28.05		TAU_HUMAN (1-758): 6.41e-90: 300: 100.00
+	Hs
		529955 A16L1_HUMAN (835-918): 9.44e-13: 73.9: 21.43		TAU_HUMAN (1-758): 6.41e-90: 300: 100.00
+	Hs
		984123 GBB2_HUMAN (563-916): 2.61e-78: 260: 20.17		SPEG_HUMAN (183-564): 2.89e-23: 108: 16.71
+	Mm
		530763 GNB5_MOUSE (645-874): 2.83e-14: 77.8: 27.31		TAU_MOUSE (1-758): 8.57e-72: 250: 70.17
+	Hs
		698256 WDR5_HUMAN (485-827): 1.58e-75: 252: 15.58		MAP4_HUMAN (22-721): 3.01e-10: 66.2: 9.24
+	Hs
		965173 WDR5_HUMAN (485-827): 1.58e-75: 252: 15.58		CIC_HUMAN (10-717): 9.83e-10: 64.7: 8.46
+	Hs
		161443 WDR5_HUMAN (485-827): 1.58e-75: 252: 15.58		KMT2D_HUMAN (3-747): 3.75e-09: 62.7: 10.76
+	Hs
		965097 WDR5_HUMAN (485-827): 1.58e-75: 252: 15.58		KMT2C_HUMAN (228-752): 7.28e-09: 62: 7.94
+	Mm
		965395 WDR5_MOUSE (485-827): 1.58e-75: 252: 15.58		KMT2C_MOUSE (228-587): 6.08e-09: 61.9: 16.84
+	Hs
		1129693 SNR40_HUMAN (555-872): 2.69e-50: 183: 16.26		MDC1_HUMAN (31-732): 1.31e-18: 93.5: 10.48
+	Hs
		161486 WDR5B_HUMAN (445-781): 2.46e-59: 207: 15.12		KMT2D_HUMAN (3-747): 3.75e-09: 62.7: 10.76
+	Hs
		161490 POC1A_HUMAN (485-781): 5.43e-58: 206: 18.91		KMT2D_HUMAN (3-747): 3.75e-09: 62.7: 10.76
+	Mm
		693433 A16L1_MOUSE (836-918): 7.87e-12: 71.3: 22.89		MAP4_MOUSE (11-720): 3.02e-34: 143: 17.29
+	Hs
		1153515 A16L1_HUMAN (835-918): 9.44e-13: 73.9: 21.43		SPEG_HUMAN (183-564): 2.89e-23: 108: 16.71
+	Hs
		698302 A16L1_HUMAN (835-918): 9.44e-13: 73.9: 21.43		MAP4_HUMAN (22-721): 3.01e-10: 66.2: 9.24
+	Mm
		1297803 A16L1_MOUSE (836-918): 7.87e-12: 71.3: 22.89		TARA_MOUSE (9-757): 1.05e-09: 64.3: 8.68
+	Hs
		1149790 TAF5_HUMAN (702-915): 3.23e-10: 66.2: 25.88		CIC_HUMAN (10-717): 9.83e-10: 64.7: 8.46