HitPredict

Interactor 1: BAG2 (O95816)
BAG family molecular chaperone regulator 2 (BAG-2) (Bcl-2-associated athanogene 2)
Gene: BAG2

Interactor 2: EP300 (Q09472)
Histone acetyltransferase p300 (p300 HAT) (EC 2.3.1.48) (E1A-associated protein p300) (Histone butyryltransferase p300) (EC 2.3.1.-) (Histone crotonyltransferase p300) (EC 2.3.1.-) (Protein 2-hydroxyisobutyryltransferase p300) (EC 2.3.1.-) (Protein lactyltransferas p300) (EC 2.3.1.-) (Protein propionyltransferase p300) (EC 2.3.1.-)
Gene: EP300

Species: Homo sapiens

Source: intact

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.47	0.60	0.536

Property	Details
Experiments	33961781
Identification Methods	affinity chromatography technology, anti tag coimmunoprecipitation
Interaction Type	physical association, association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0005829 - cytosol GO:0048156 - tau protein binding GO:0050821 - protein stabilization
Homologous interactions	9

Homologous interactions

Color coding for hit scores

	1 211 Hs			1 2414
+	Hs
		324121 BAG2_HUMAN (1-211): 3e-99: 288: 100.00		TRI33_HUMAN (604-1201): 1.37e-44: 180: 14.50
+	Hs
		164342 BAG2_HUMAN (1-211): 3e-99: 288: 100.00		TRI66_HUMAN (268-1197): 1.08e-40: 168: 12.26
+	Hs
		323593 BAG2_HUMAN (1-211): 3e-99: 288: 100.00		BRD2_HUMAN (1035-1159): 9.57e-30: 131: 31.20
+	Hs
		323769 BAG2_HUMAN (1-211): 3e-99: 288: 100.00		BRD3_HUMAN (1055-1159): 9.06e-30: 130: 30.48
+	Hs
		324021 BAG2_HUMAN (1-211): 3e-99: 288: 100.00		BRD8_HUMAN (965-1183): 9.91e-16: 86: 19.18
+	Hs
		323717 BAG2_HUMAN (1-211): 3e-99: 288: 100.00		BPTF_HUMAN (2011-2413): 1.11e-14: 82.9: 12.86
+	Hs
		323756 BAG2_HUMAN (1-211): 3e-99: 288: 100.00		MDC1_HUMAN (455-1061): 8.69e-13: 76.6: 11.82
+	Hs
		323843 BAG2_HUMAN (1-211): 3e-99: 288: 100.00		BRWD3_HUMAN (1006-1157): 1.89e-10: 68.9: 27.93
+	Hs
		323936 BAG2_HUMAN (1-211): 3e-99: 288: 100.00		CBP_HUMAN (1752-2400): 4.44e-10: 67.9: 13.25