HitPredict

Interactor 1: AIFM1 (O95831)
Apoptosis-inducing factor 1, mitochondrial (EC 1.6.99.-) (Programmed cell death protein 8)
Gene: AIFM1

Interactor 2: SCMC2 (Q6KCM7)
Mitochondrial adenyl nucleotide antiporter SLC25A25 (Mitochondrial ATP-Mg/Pi carrier protein 3) (Mitochondrial Ca(2+)-dependent solute carrier protein 3) (Short calcium-binding mitochondrial carrier protein 2) (SCaMC-2) (Solute carrier family 25 member 25)
Gene: SLC25A25

Species: Homo sapiens

Source: biogrid

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.56	0.60	0.584

Property	Details
Experiments	29568061, 34079125
Identification Methods	proximity labelling technology
Interaction Type	physical association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0005739 - mitochondrion GO:0005743 - mitochondrial inner membrane
Homologous interactions	6

Homologous interactions

Color coding for hit scores

	1 613 Hs			1 469
+	Hs
		325229 AIFM1_HUMAN (1-613): 0: 581: 100.00		SCMC1_HUMAN (5-469): 1.06e-144: 424: 60.43
+	Hs
		325363 AIFM1_HUMAN (1-613): 0: 581: 100.00		SCMC3_HUMAN (9-469): 8.68e-140: 411: 64.64
+	Hs
		325209 AIFM1_HUMAN (1-613): 0: 581: 100.00		KMCP1_HUMAN (185-363): 2.46e-40: 148: 25.81
+	Hs
		325450 AIFM1_HUMAN (1-613): 0: 581: 100.00		S2513_HUMAN (166-283): 1.86e-17: 87: 22.50
+	Hs
		274463 AIFM1_HUMAN (1-613): 0: 581: 100.00		S2512_HUMAN (166-283): 7.41e-17: 85.4: 21.67
+	Hs
		324989 AIFM1_HUMAN (1-613): 0: 581: 100.00		ADT2_HUMAN (370-469): 9.11e-14: 73.5: 16.04