Protein: SEM4G
Semaphorin-4G

Gene: SEM4G, SEMA4G
Organism: Homo sapiens
Interactions: 75
UniProt ID: Q9NTN9

Gene Ontology (top 5):
GO:0001755 - neural crest cell migration
GO:0005886 - plasma membrane
GO:0007411 - axon guidance
GO:0030215 - semaphorin receptor binding
GO:0030335 - positive regulation of cell migration

Download interactions: TXT   MITAB-2.5

Interaction Interactor Experiments Homologs Category Interaction
Score
Confidence

351731

SG1D1
Secretoglobin family 1D member 1

2

3

High-throughput

0.726

High

1449615

BTNL2
Butyrophilin-like protein 2

1

5

High-throughput

0.691

High

178660

DEGS1
Sphingolipid delta(4)-desaturase DES1

2

0

High-throughput

0.580

High

1449613

TR10D
Tumor necrosis factor receptor superfamily member 10D

2

0

High-throughput

0.580

High

1151091

PCH2
Pachytene checkpoint protein 2 homolog

2

1

High-throughput

0.578

High

1372097

RBPMS
RNA-binding protein with multiple splicing

2

1

High-throughput

0.578

High

399467

TRGV3
T cell receptor gamma variable 3

1

1

High-throughput

0.575

High

1439564

GOPC
Golgi-associated PDZ and coiled-coil motif-containing protein

1

9

High-throughput

0.573

High

1187577

AR13B
ADP-ribosylation factor-like protein 13B

2

2

High-throughput

0.553

High

1384363

CR3L1
Cyclic AMP-responsive element-binding protein 3-like protein 1

2

1

High-throughput

0.553

High

64388

CDHR4
Cadherin-related family member 4

1

10

High-throughput

0.536

High

380366

DRA
HLA class II histocompatibility antigen, DR alpha chain

1

11

High-throughput

0.536

High

593510

PGFRA
Platelet-derived growth factor receptor alpha

1

8

High-throughput

0.536

High

607421

HLAG
HLA class I histocompatibility antigen, alpha chain G

1

4

High-throughput

0.536

High

1030219

IL5RA
Interleukin-5 receptor subunit alpha

1

4

High-throughput

0.536

High

1116310

PTC1
Protein patched homolog 1

1

9

High-throughput

0.536

High

1147447

EPHA7
Ephrin type-A receptor 7

1

6

High-throughput

0.536

High

1382069

T106A
Transmembrane protein 106A

1

5

High-throughput

0.536

High

1390889

ASIC4
Acid-sensing ion channel 4

1

2

High-throughput

0.536

High

1449620

PCDB3
Protocadherin beta-3

1

5

High-throughput

0.536

High

650445

FGFR3
Fibroblast growth factor receptor 3

1

6

High-throughput

0.515

High

1096506

PAK1
Serine/threonine-protein kinase PAK 1

1

1

High-throughput

0.515

High

1133926

NMDE3
Glutamate receptor ionotropic, NMDA 2C

1

1

High-throughput

0.515

High

1449618

UBQL1
Ubiquilin-1

1

1

High-throughput

0.515

High

1307656

ZDH17
Palmitoyltransferase ZDHHC17

1

2

High-throughput

0.494

High

442489

GELS
Gelsolin

1

0

High-throughput

0.493

High

562435

LAMP2
Lysosome-associated membrane glycoprotein 2

1

0

High-throughput

0.493

High

705572

GRN
Progranulin

1

0

High-throughput

0.493

High

720060

HMOX2
Heme oxygenase 2

1

0

High-throughput

0.493

High

86042

IGLL5
Immunoglobulin lambda-like polypeptide 5

1

8

High-throughput

0.489

High

342675

LY86
Lymphocyte antigen 86

1

4

High-throughput

0.489

High

455667

KLK3
Prostate-specific antigen

1

12

High-throughput

0.489

High

548127

PSPC
Surfactant protein C

1

4

High-throughput

0.489

High

567994

PRG2
Bone marrow proteoglycan

1

6

High-throughput

0.489

High

880066

DNSL1
Deoxyribonuclease-1-like 1

1

3

High-throughput

0.489

High

933231

SLUR1
Secreted Ly-6/uPAR-related protein 1

1

4

High-throughput

0.489

High

976867

LCN6
Epididymal-specific lipocalin-6

1

3

High-throughput

0.489

High

1347298

FIBIN
Fin bud initiation factor homolog

1

3

High-throughput

0.489

High

1359256

CA054
Uncharacterized protein C1orf54

1

6

High-throughput

0.489

High

1369070

GGH
Gamma-glutamyl hydrolase

1

2

High-throughput

0.489

High

1392305

ZDH12
Palmitoyltransferase ZDHHC12

1

4

High-throughput

0.489

High

1430752

CST11
Cystatin-11

1

5

High-throughput

0.489

High

1432755

TMX1
Thioredoxin-related transmembrane protein 1

1

5

High-throughput

0.489

High

1439359

SDF2L
Stromal cell-derived factor 2-like protein 1

1

6

High-throughput

0.489

High

1449612

CBLN4
Cerebellin-4

1

9

High-throughput

0.489

High

1449614

DNJB9
DnaJ homolog subfamily B member 9

1

5

High-throughput

0.489

High

1449617

FBX2
F-box only protein 2

1

11

High-throughput

0.489

High

1449616

DBNL
Drebrin-like protein

1

1

High-throughput

0.479

High

231768

PEX1
Peroxisomal ATPase PEX1

1

1

High-throughput

0.470

High

246157

KIF1B
Kinesin-like protein KIF1B

1

3

High-throughput

0.470

High

280841

PR40A
Pre-mRNA-processing factor 40 homolog A

1

5

High-throughput

0.470

High

301723

WFS1
Wolframin

1

1

High-throughput

0.470

High

384561

CRYAA
Alpha-crystallin A chain

1

1

High-throughput

0.470

High

415887

HSPB1
Heat shock protein beta-1

1

1

High-throughput

0.470

High

981716

RAN
GTP-binding nuclear protein Ran

1

5

High-throughput

0.470

High

1289896

Q86V38
Atrophin 1

1

1

High-throughput

0.470

High

1369706

KLK6
Kallikrein-6

1

12

High-throughput

0.470

High

1449619

RNF11
RING finger protein 11

1

1

High-throughput

0.470

High

1242953

S39A4
Zinc transporter ZIP4

1

6

High-throughput

0.445

High

243067

PRKN
E3 ubiquitin-protein ligase parkin

1

2

High-throughput

0.437

High

166427

ZNT4
Probable proton-coupled zinc antiporter SLC30A4

1

0

High-throughput

0.426

High

948943

CD81
CD81 antigen

1

0

High-throughput

0.426

High

1110302

KCC2B
Calcium/calmodulin-dependent protein kinase type II subunit beta

1

0

High-throughput

0.299

High

927573

ATX1
Ataxin-1

1

0

High-throughput

0.282

High

946595

EVA1C
Protein eva-1 homolog C

1

0

High-throughput

0.279

Low

1138091

TNIP1
TNFAIP3-interacting protein 1

1

0

High-throughput

0.279

Low

1429989

SHRPN
Sharpin

1

0

High-throughput

0.279

Low

47422

A0A6Q8PF08
Peripheral myelin protein 22

1

0

High-throughput

0.268

Low

876197

TCPE
T-complex protein 1 subunit epsilon

1

0

High-throughput

0.268

Low

937122

CASP6
Caspase-6

1

0

High-throughput

0.268

Low

954624

PRPS1
Ribose-phosphate pyrophosphokinase 1

1

0

High-throughput

0.268

Low

1023627

CYC
Cytochrome c

1

0

High-throughput

0.268

Low

1341329

COQ8A
Atypical kinase COQ8A, mitochondrial

1

0

High-throughput

0.268

Low

1449621

Q9Y649
GW128

1

0

High-throughput

0.268

Low

892728

DNLI4
DNA ligase 4

1

0

High-throughput

0.251

Low


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Last updated: 11Aug2025