HitPredict

Interactor 1: LATS1 (O95835)
Serine/threonine-protein kinase LATS1 (EC 2.7.11.1) (Large tumor suppressor homolog 1) (WARTS protein kinase) (h-warts)
Gene: LATS1

Interactor 2: K1C17 (Q04695)
Keratin, type I cytoskeletal 17 (39.1) (Cytokeratin-17) (CK-17) (Keratin-17) (K17)
Gene: KRT17

Species: Homo sapiens

Source: biogrid

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.38	0.60	0.479

Property	Details
Experiments	35941108
Identification Methods	affinity chromatography technology
Interaction Type	physical association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0005829 - cytosol
Homologous interactions	11

Homologous interactions

Color coding for hit scores

	1 1130 Hs			1 432
+	Hs
		325601 LATS1_HUMAN (1-1130): 0: 934: 100.00		K1C16_HUMAN (80-410): 1.7e-159: 460: 79.28
+	Hs
		325794 LATS1_HUMAN (1-1130): 0: 934: 100.00		K2C73_HUMAN (4-398): 3.6e-88: 279: 25.68
+	Hs
		325740 LATS1_HUMAN (1-1130): 0: 934: 100.00		K1H1_HUMAN (39-405): 3.5e-84: 265: 53.13
+	Hs
		325658 LATS1_HUMAN (1-1130): 0: 934: 100.00		K2C6C_HUMAN (50-398): 4.63e-73: 241: 23.93
+	Hs
		325613 LATS1_HUMAN (1-1130): 0: 934: 100.00		K2C5_HUMAN (50-398): 1.34e-72: 240: 25.07
+	Hs
		325582 LATS1_HUMAN (1-1130): 0: 934: 100.00		K2C6A_HUMAN (50-414): 3.75e-72: 238: 23.71
+	Hs
		531325 AKT1_HUMAN (595-1081): 5.84e-141: 435: 24.50		K1C10_HUMAN (79-389): 1.15e-123: 372: 69.75
+	Hs
		1071451 ST38L_HUMAN (627-1089): 2.37e-167: 503: 40.82		K1H1_HUMAN (39-405): 3.5e-84: 265: 53.13
+	Hs
		1055200 AKT3_HUMAN (603-1081): 5.7e-143: 440: 24.54		K1H2_HUMAN (1-395): 5.85e-80: 255: 50.13
+	Hs
		681844 AKT1_HUMAN (595-1081): 5.84e-141: 435: 24.50		K1H2_HUMAN (1-395): 5.85e-80: 255: 50.13
+	Hs
		1071229 Q6PJG3_HUMAN (1-117): 2.14e-61: 207: 99.15		K1H1_HUMAN (39-405): 3.5e-84: 265: 53.13