HitPredict

Interactor 1: LATS1 (O95835)
Serine/threonine-protein kinase LATS1 (EC 2.7.11.1) (Large tumor suppressor homolog 1) (WARTS protein kinase) (h-warts)
Gene: LATS1

Interactor 2: NIN (Q8N4C6)
Ninein (hNinein) (Glycogen synthase kinase 3 beta-interacting protein) (GSK3B-interacting protein)
Gene: NIN

Species: Homo sapiens

Source: biogrid

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.56	0.60	0.584

Property	Details
Experiments	28718761, 34079125
Identification Methods	proximity labelling technology
Interaction Type	physical association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0000922 - spindle pole GO:0005813 - centrosome
Homologous interactions	20

Homologous interactions (Top 20)

Color coding for hit scores

	1 1130 Hs			1 2090
+	Hs
		1233464 LATS2_HUMAN (13-1121): 0: 751: 49.61		NIN_HUMAN (1-2090): 0: 617: 100.00
+	Hs
		325612 LATS1_HUMAN (1-1130): 0: 934: 100.00		MYH8_HUMAN (111-1154): 9.6e-31: 135: 11.88
+	Hs
		325608 LATS1_HUMAN (1-1130): 0: 934: 100.00		MYH1_HUMAN (1262-2078): 3.82e-26: 120: 12.03
+	Hs
		325935 LATS1_HUMAN (1-1130): 0: 934: 100.00		MYH2_HUMAN (1494-2089): 3.74e-23: 110: 11.35
+	Hs
		325955 LATS1_HUMAN (1-1130): 0: 934: 100.00		MYH4_HUMAN (1282-2050): 5.42e-19: 96.7: 12.82
+	Hs
		166653 LATS1_HUMAN (1-1130): 0: 934: 100.00		CE290_HUMAN (1326-2090): 1.25e-17: 92.4: 9.75
+	Hs
		325737 LATS1_HUMAN (1-1130): 0: 934: 100.00		PLEC_HUMAN (320-1163): 1.13e-15: 86.3: 13.21
+	Hs
		325611 LATS1_HUMAN (1-1130): 0: 934: 100.00		MYH6_HUMAN (1342-2059): 1.88e-14: 82.1: 13.91
+	Hs
		325605 LATS1_HUMAN (1-1130): 0: 934: 100.00		MYH3_HUMAN (1331-2059): 2.04e-14: 81.7: 14.38
+	Hs
		325936 LATS1_HUMAN (1-1130): 0: 934: 100.00		MYH13_HUMAN (1382-2076): 5.15e-14: 80.5: 14.35
+	Hs
		325609 LATS1_HUMAN (1-1130): 0: 934: 100.00		MYH7_HUMAN (127-785): 5.86e-14: 80.4: 12.17
+	Hs
		325946 LATS1_HUMAN (1-1130): 0: 934: 100.00		NINL_HUMAN (1044-2050): 5.99e-09: 63.9: 9.93
+	Hs
		1344979 LATS2_HUMAN (13-1121): 0: 751: 49.61		NINL_HUMAN (1044-2050): 5.99e-09: 63.9: 9.93
+	Hs
		725079 ST38L_HUMAN (627-1089): 2.37e-167: 503: 40.82		MYH9_HUMAN (37-778): 5.44e-23: 110: 11.55
+	Dm
		1213452 WARTS_DROME (161-1065): 1.96e-152: 486: 39.48		Q8INC3_DROME (413-1072): 1.12e-13: 79.4: 20.31
+	Dm
		1001877 WARTS_DROME (161-1065): 1.96e-152: 486: 39.48		Q0KI67_DROME (413-1072): 2.44e-13: 78.3: 20.31
+	Hs
		518814 KAPCA_HUMAN (661-1058): 6.14e-138: 422: 31.59		TPR_HUMAN (30-1095): 7.67e-28: 126: 10.73
+	Hs
		681696 AKT1_HUMAN (595-1081): 5.84e-141: 435: 24.50		MYH9_HUMAN (37-778): 5.44e-23: 110: 11.55
+	Hs
		568567 KAPCA_HUMAN (661-1058): 6.14e-138: 422: 31.59		MYH9_HUMAN (37-778): 5.44e-23: 110: 11.55
+	Hs
		551616 AKT1_HUMAN (595-1081): 5.84e-141: 435: 24.50		DESP_HUMAN (1122-2071): 1.98e-15: 85.1: 11.54