HitPredict

Interactor 1: LATS1 (O95835)
Serine/threonine-protein kinase LATS1 (EC 2.7.11.1) (Large tumor suppressor homolog 1) (WARTS protein kinase) (h-warts)
Gene: LATS1

Interactor 2: AKAP9 (Q99996)
A-kinase anchor protein 9 (AKAP-9) (A-kinase anchor protein 350 kDa) (AKAP 350) (hgAKAP 350) (A-kinase anchor protein 450 kDa) (AKAP 450) (AKAP 120-like protein) (Centrosome- and Golgi-localized PKN-associated protein) (CG-NAP) (Protein hyperion) (Protein kinase A-anchoring protein 9) (PRKA9) (Protein yotiao)
Gene: AKAP9

Species: Homo sapiens

Source: biogrid

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.38	0.60	0.479

Property	Details
Experiments	34079125
Identification Methods	proximity labelling technology
Interaction Type	physical association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0005813 - centrosome GO:0005829 - cytosol GO:0033138 - positive regulation of peptidyl-serine phosphorylation
Homologous interactions	20

Homologous interactions (Top 20)

Color coding for hit scores

	1 1130 Hs			1 3907
+	Hs
		568780 KAPCA_HUMAN (661-1058): 6.14e-138: 422: 31.59		AKAP9_HUMAN (1-3907): 0: 878: 100.00
+	Hs
		166653 LATS1_HUMAN (1-1130): 0: 934: 100.00		CE290_HUMAN (2108-3900): 1.69e-42: 175: 10.38
+	Hs
		325611 LATS1_HUMAN (1-1130): 0: 934: 100.00		MYH6_HUMAN (571-1660): 2.29e-37: 158: 10.35
+	Hs
		325737 LATS1_HUMAN (1-1130): 0: 934: 100.00		PLEC_HUMAN (2053-3720): 9.98e-35: 150: 11.45
+	Hs
		325605 LATS1_HUMAN (1-1130): 0: 934: 100.00		MYH3_HUMAN (2796-3744): 4.53e-31: 137: 11.53
+	Hs
		325955 LATS1_HUMAN (1-1130): 0: 934: 100.00		MYH4_HUMAN (3383-3898): 9.59e-16: 87: 8.43
+	Hs
		325609 LATS1_HUMAN (1-1130): 0: 934: 100.00		MYH7_HUMAN (3369-3901): 1.83e-15: 86.3: 8.52
+	Hs
		325935 LATS1_HUMAN (1-1130): 0: 934: 100.00		MYH2_HUMAN (3460-3897): 1.17e-12: 77: 7.85
+	Hs
		325608 LATS1_HUMAN (1-1130): 0: 934: 100.00		MYH1_HUMAN (3439-3893): 6.81e-12: 74.3: 7.56
+	Hs
		317194 LATS1_HUMAN (1-1130): 0: 934: 100.00		PCNT_HUMAN (220-863): 6.95e-11: 71.2: 11.28
+	Hs
		325612 LATS1_HUMAN (1-1130): 0: 934: 100.00		MYH8_HUMAN (3-418): 3.51e-09: 65.5: 10.79
+	Hs
		325919 LATS1_HUMAN (1-1130): 0: 934: 100.00		DAPLE_HUMAN (2137-2753): 8.15e-09: 64.2: 14.04
+	Hs
		149340 LATS2_HUMAN (13-1121): 0: 751: 49.61		CTRO_HUMAN (18-648): 1.78e-09: 66.5: 12.83
+	Hs
		1344953 LATS2_HUMAN (13-1121): 0: 751: 49.61		DAPLE_HUMAN (2137-2753): 8.15e-09: 64.2: 14.04
+	Hs
		725079 ST38L_HUMAN (627-1089): 2.37e-167: 503: 40.82		MYH9_HUMAN (135-781): 3.02e-14: 82.3: 15.29
+	Hs
		681696 AKT1_HUMAN (595-1081): 5.84e-141: 435: 24.50		MYH9_HUMAN (135-781): 3.02e-14: 82.3: 15.29
+	Hs
		568567 KAPCA_HUMAN (661-1058): 6.14e-138: 422: 31.59		MYH9_HUMAN (135-781): 3.02e-14: 82.3: 15.29
+	Hs
		551616 AKT1_HUMAN (595-1081): 5.84e-141: 435: 24.50		DESP_HUMAN (2135-3311): 1.98e-09: 66.5: 13.94
+	Hs
		317209 KAPCA_HUMAN (661-1058): 6.14e-138: 422: 31.59		PCNT_HUMAN (220-863): 6.95e-11: 71.2: 11.28
+	Hs
		522538 KAPCB_HUMAN (661-1055): 5.19e-133: 410: 31.58		MYH1_HUMAN (3439-3893): 6.81e-12: 74.3: 7.56