HitPredict

Interactor 1: GBRAP (O95166)
Gamma-aminobutyric acid receptor-associated protein (GABA(A) receptor-associated protein) (MM46)
Gene: GABARAP

Interactor 2: TBC15 (Q8TC07)
TBC1 domain family member 15 (GTPase-activating protein RAB7) (GAP for RAB7) (Rab7-GAP)
Gene: TBC1D15

Species: Homo sapiens

Source: intact

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.57	0.50	0.535

Property	Details
Experiments	20562859
Identification Methods	affinity chromatography technology, pull down, anti tag coimmunoprecipitation
Interaction Type	physical association, direct interaction, association

Property	Details
Interacting Pfam domains	-
Common GO terms	-
Homologous interactions	20

Homologous interactions (Top 20)

Color coding for hit scores

	1 117 Hs			1 691
+	Hs
		952254 GBRL2_HUMAN (1-117): 2.76e-58: 176: 57.27		TBC15_HUMAN (1-691): 0: 692: 100.00
+	Hs
		1349327 GBRL1_HUMAN (1-116): 8.18e-56: 170: 87.07		TBC15_HUMAN (1-691): 0: 692: 100.00
+	Hs
		1430332 GBRL1_HUMAN (1-116): 8.18e-56: 170: 87.07		TBC17_HUMAN (1-644): 1.79e-176: 519: 47.45
+	Dm
		1472745 Q9VEG5_DROME (1-116): 5.37e-54: 166: 77.59		Q9VPL5_DROME (8-629): 2.8e-132: 408: 31.81
+	Hs
		952196 GBRL2_HUMAN (1-117): 2.76e-58: 176: 57.27		TBC25_HUMAN (308-559): 4.76e-89: 294: 37.95
+	Hs
		328037 GBRAP_HUMAN (1-117): 8.09e-57: 173: 100.00		TBC25_HUMAN (308-559): 4.76e-89: 294: 37.95
+	Hs
		1187137 GBRL1_HUMAN (1-116): 8.18e-56: 170: 87.07		TBC25_HUMAN (308-559): 4.76e-89: 294: 37.95
+	Hs
		1349065 GBRL1_HUMAN (1-116): 8.18e-56: 170: 87.07		TBC16_HUMAN (271-667): 1.47e-87: 292: 28.88
+	Hs
		952205 GBRL2_HUMAN (1-117): 2.76e-58: 176: 57.27		TBC9B_HUMAN (196-671): 5.62e-80: 279: 14.85
+	Hs
		952218 GBRL2_HUMAN (1-117): 2.76e-58: 176: 57.27		TBCD9_HUMAN (196-659): 2.98e-80: 279: 13.53
+	Hs
		1195312 GBRL1_HUMAN (1-116): 8.18e-56: 170: 87.07		TB10B_HUMAN (212-670): 5.74e-83: 281: 15.92
+	Hs
		1226423 GBRL1_HUMAN (1-116): 8.18e-56: 170: 87.07		TBC9B_HUMAN (196-671): 5.62e-80: 279: 14.85
+	Hs
		1254235 GBRL1_HUMAN (1-116): 8.18e-56: 170: 87.07		TBCD9_HUMAN (196-659): 2.98e-80: 279: 13.53
+	Sc
		795572 ATG8_YEAST (1-116): 9.22e-59: 178: 55.17		GYP1_YEAST (285-557): 1.13e-79: 268: 22.85
+	Hs
		1187138 MLP3A_HUMAN (5-117): 2.3e-45: 144: 30.44		TBC25_HUMAN (308-559): 4.76e-89: 294: 37.95
+	Hs
		1287255 GBRL1_HUMAN (1-116): 8.18e-56: 170: 87.07		TBCD1_HUMAN (198-649): 1.55e-76: 268: 17.92
+	Hs
		1416800 GBRL1_HUMAN (1-116): 8.18e-56: 170: 87.07		TB10A_HUMAN (254-681): 2.45e-80: 266: 18.40
+	Hs
		1195313 MLP3A_HUMAN (5-117): 2.3e-45: 144: 30.44		TB10B_HUMAN (212-670): 5.74e-83: 281: 15.92
+	Hs
		1226424 MLP3A_HUMAN (5-117): 2.3e-45: 144: 30.44		TBC9B_HUMAN (196-671): 5.62e-80: 279: 14.85
+	Hs
		1254237 MLP3A_HUMAN (5-117): 2.3e-45: 144: 30.44		TBCD9_HUMAN (196-659): 2.98e-80: 279: 13.53