HitPredict

Interactor 1: TBC25 (Q3MII6)
TBC1 domain family member 25
Gene: TBC1D25

Interactor 2: GBRL1 (Q9H0R8)
Gamma-aminobutyric acid receptor-associated protein-like 1 (Early estrogen-regulated protein) (GABA(A) receptor-associated protein-like 1) (Glandular epithelial cell protein 1) (GEC-1)
Gene: GABARAPL1

Species: Homo sapiens

Source: intact

Category: Small-scale

Confidence: High

Method score	Annotation score	Interaction score
0.87	0.60	0.724

Property	Details
Experiments	28514442, 32296183, 33961781, 22354992, unassigned1304
Identification Methods	affinity chromatography technology, two hybrid, pull down, two hybrid array, two hybrid prey pooling approach, anti tag coimmunoprecipitation, validated two hybrid
Interaction Type	physical association, direct interaction, association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0005776 - autophagosome
Homologous interactions	20

Homologous interactions (Top 20)

Color coding for hit scores

	1 688 Hs			1 117
+	Hs
		952196 TBC25_HUMAN (1-688): 0: 735: 100.00		GBRL2_HUMAN (1-116): 1.39e-57: 175: 61.21
+	Hs
		328037 TBC25_HUMAN (1-688): 0: 735: 100.00		GBRAP_HUMAN (1-116): 2.97e-56: 171: 87.07
+	Hs
		1187135 TBC25_HUMAN (1-688): 0: 735: 100.00		MLP3C_HUMAN (5-116): 1.62e-44: 143: 39.47
+	Hs
		1187138 TBC25_HUMAN (1-688): 0: 735: 100.00		MLP3A_HUMAN (5-116): 1.1e-44: 142: 34.21
+	Hs
		1187136 TBC25_HUMAN (1-688): 0: 735: 100.00		MLP3B_HUMAN (2-116): 1.06e-43: 140: 31.62
+	Hs
		1416800 TB10A_HUMAN (127-614): 4.14e-95: 305: 16.53		GBRL1_HUMAN (1-117): 4.56e-56: 171: 100.00
+	Hs
		952254 TBC15_HUMAN (137-475): 2.56e-86: 287: 31.11		GBRL2_HUMAN (1-116): 1.39e-57: 175: 61.21
+	Hs
		1349327 TBC15_HUMAN (137-475): 2.56e-86: 287: 31.11		GBRL1_HUMAN (1-117): 4.56e-56: 171: 100.00
+	Hs
		328077 TBC15_HUMAN (137-475): 2.56e-86: 287: 31.11		GBRAP_HUMAN (1-116): 2.97e-56: 171: 87.07
+	Hs
		1416801 TB10A_HUMAN (127-614): 4.14e-95: 305: 16.53		MLP3A_HUMAN (5-116): 1.1e-44: 142: 34.21
+	Dm
		1472745 Q9VPL5_DROME (112-475): 1.8e-78: 266: 27.08		Q9VEG5_DROME (1-117): 1.87e-54: 167: 73.50
+	Hs
		1287255 TBCD1_HUMAN (78-609): 9.43e-74: 260: 16.42		GBRL1_HUMAN (1-117): 4.56e-56: 171: 100.00
+	Hs
		1349321 TBC15_HUMAN (137-475): 2.56e-86: 287: 31.11		MLP3C_HUMAN (5-116): 1.62e-44: 143: 39.47
+	Hs
		1349323 TBC15_HUMAN (137-475): 2.56e-86: 287: 31.11		MLP3B_HUMAN (2-116): 1.06e-43: 140: 31.62
+	Hs
		1195312 TB10B_HUMAN (114-617): 1.79e-72: 252: 15.89		GBRL1_HUMAN (1-117): 4.56e-56: 171: 100.00
+	Hs
		1430332 TBC17_HUMAN (194-550): 1.7e-72: 249: 31.22		GBRL1_HUMAN (1-117): 4.56e-56: 171: 100.00
+	Hs
		1287256 TBCD1_HUMAN (78-609): 9.43e-74: 260: 16.42		MLP3A_HUMAN (5-116): 1.1e-44: 142: 34.21
+	Hs
		1195313 TB10B_HUMAN (114-617): 1.79e-72: 252: 15.89		MLP3A_HUMAN (5-116): 1.1e-44: 142: 34.21
+	Hs
		1433200 TBC17_HUMAN (194-550): 1.7e-72: 249: 31.22		MLP3A_HUMAN (5-116): 1.1e-44: 142: 34.21
+	Hs
		1428363 TBC17_HUMAN (194-550): 1.7e-72: 249: 31.22		MLP3B_HUMAN (2-116): 1.06e-43: 140: 31.62