Interactor 1: APCL (O95996)
Adenomatous polyposis coli protein 2 (Adenomatous polyposis coli protein-like) (APC-like)
Gene: APC2

Interactor 2: CTNB1 (P35222)
Catenin beta-1 (Beta-catenin)
Gene: CTNNB1

Species: Homo sapiens

Source: biogrid

Category: Small-scale

Confidence: High

Method score Annotation score Interaction score
0.77 1.00 0.882

The method score is based on:

Property Details
Experiments 9823329, 16510875, 10074433, 23840886
Identification Methods pull down, two hybrid, affinity chromatography technology
Interaction Type direct interaction, physical association

The annotation score is based on:

Property Details
Interacting Pfam domains APC_rep~Arm, Arm~Arm
Common GO terms GO:0001708 - cell fate specification
GO:0005737 - cytoplasm
GO:0005829 - cytosol
GO:0016342 - catenin complex
GO:0030877 - beta-catenin destruction complex
and 3 others

more...

Homologous interactions 20

Homologous interactions (Top 20)

Color coding for hit scores

1 2303
Hs

1 781
+ Mm
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+ Rn
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+ Dm
+ Dm
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+ Mm
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+ Ce
+ Ce
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+ Hs

Service provided by Combinatics, Japan

Last updated: 15 Jul 2024