HitPredict

Interactor 1: IPO7 (O95373)
Importin-7 (Imp7) (Ran-binding protein 7) (RanBP7)
Gene: IPO7

Interactor 2: EGFR (P00533)
Epidermal growth factor receptor (EC 2.7.10.1) (Proto-oncogene c-ErbB-1) (Receptor tyrosine-protein kinase erbB-1)
Gene: EGFR

Species: Homo sapiens

Source: biogrid

Category: Small-scale

Confidence: High

Method score	Annotation score	Interaction score
0.56	0.60	0.584

Property	Details
Experiments	25754235, 23956138
Identification Methods	affinity chromatography technology
Interaction Type	physical association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0005829 - cytosol GO:0016020 - membrane
Homologous interactions	12

Homologous interactions

Color coding for hit scores

	1 1038 Hs			1 1210
+	Hs
		189085 IPO8_HUMAN (1-1032): 0: 827: 64.41		EGFR_HUMAN (1-1210): 0: 1246: 100.00
+	Hs
		363037 XPO2_HUMAN (2-921): 3.98e-168: 521: 17.89		EGFR_HUMAN (1-1210): 0: 1246: 100.00
+	Hs
		363673 TNPO1_HUMAN (12-906): 4.14e-125: 405: 13.62		EGFR_HUMAN (1-1210): 0: 1246: 100.00
+	Hs
		363989 IPO11_HUMAN (1-951): 5.64e-123: 401: 15.82		EGFR_HUMAN (1-1210): 0: 1246: 100.00
+	Hs
		363732 IPO9_HUMAN (4-995): 1.53e-121: 399: 14.68		EGFR_HUMAN (1-1210): 0: 1246: 100.00
+	Hs
		133913 IPO5_HUMAN (4-910): 2.44e-118: 392: 12.12		EGFR_HUMAN (1-1210): 0: 1246: 100.00
+	Hs
		164505 TNPO2_HUMAN (12-906): 1.97e-119: 390: 12.80		EGFR_HUMAN (1-1210): 0: 1246: 100.00
+	Hs
		363302 IMB1_HUMAN (5-875): 6.55e-116: 380: 12.95		EGFR_HUMAN (1-1210): 0: 1246: 100.00
+	Hs
		410979 TNPO1_HUMAN (12-906): 4.14e-125: 405: 13.62		ERBB2_HUMAN (5-1203): 0: 1119: 48.38
+	Hs
		410852 IMB1_HUMAN (5-875): 6.55e-116: 380: 12.95		ERBB2_HUMAN (5-1203): 0: 1119: 48.38
+	Hs
		465600 TNPO1_HUMAN (12-906): 4.14e-125: 405: 13.62		IGF1R_HUMAN (438-1062): 5.28e-109: 375: 20.53
+	Mm
		849118 XPO2_MOUSE (2-921): 7.12e-168: 520: 17.68		ZAP70_MOUSE (718-961): 2.04e-52: 197: 40.00