HitPredict

Interactor 1: M3K6 (O95382)
Mitogen-activated protein kinase kinase kinase 6 (EC 2.7.11.25) (Apoptosis signal-regulating kinase 2)
Gene: MAP3K6

Interactor 2: 1433Z (P63104)
14-3-3 protein zeta/delta (Protein kinase C inhibitor protein 1) (KCIP-1)
Gene: YWHAZ

Species: Homo sapiens

Source: innatedb

Category: Small-scale

Confidence: High

Method score	Annotation score	Interaction score
0.38	0.60	0.479

Property	Details
Experiments	19935702
Identification Methods	affinity chromatography technology
Interaction Type	physical association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0006468 - protein phosphorylation GO:0007165 - signal transduction
Homologous interactions	20

Homologous interactions (Top 20)

Color coding for hit scores

	1 1288 Hs			1 245
+	Hs
		335317 M3K6_HUMAN (1-1288): 0: 1359: 99.38		1433E_HUMAN (2-241): 9.95e-144: 403: 68.18
+	Hs
		335304 M3K6_HUMAN (1-1288): 0: 1359: 99.38		1433T_HUMAN (1-245): 2.61e-140: 395: 79.59
+	Hs
		335307 M3K6_HUMAN (1-1288): 0: 1359: 99.38		1433B_HUMAN (1-242): 9.05e-140: 393: 87.60
+	Hs
		335316 M3K6_HUMAN (1-1288): 0: 1359: 99.38		1433G_HUMAN (1-240): 2.38e-108: 314: 74.59
+	Hs
		335320 M3K6_HUMAN (1-1288): 0: 1359: 99.38		1433F_HUMAN (2-240): 1.27e-107: 312: 74.49
+	Hs
		335308 M3K6_HUMAN (1-1288): 0: 1359: 99.38		1433S_HUMAN (1-237): 8.31e-104: 302: 71.97
+	Hs
		990653 M3K5_HUMAN (2-1282): 0: 1193: 44.32		1433Z_HUMAN (1-245): 1.67e-144: 405: 100.00
+	Hs
		971926 M3K5_HUMAN (2-1282): 0: 1193: 44.32		1433E_HUMAN (2-241): 9.95e-144: 403: 68.18
+	Hs
		990383 M3K15_HUMAN (2-1278): 0: 1187: 43.56		1433Z_HUMAN (1-245): 1.67e-144: 405: 100.00
+	Hs
		971675 M3K15_HUMAN (2-1278): 0: 1187: 43.56		1433E_HUMAN (2-241): 9.95e-144: 403: 68.18
+	Hs
		691368 M3K5_HUMAN (2-1282): 0: 1193: 44.32		1433T_HUMAN (1-245): 2.61e-140: 395: 79.59
+	Hs
		730187 M3K5_HUMAN (2-1282): 0: 1193: 44.32		1433B_HUMAN (1-242): 9.05e-140: 393: 87.60
+	Hs
		966794 M3K5_HUMAN (2-1282): 0: 1193: 44.32		1433G_HUMAN (1-240): 2.38e-108: 314: 74.59
+	Hs
		1049707 M3K5_HUMAN (2-1282): 0: 1193: 44.32		1433F_HUMAN (2-240): 1.27e-107: 312: 74.49
+	Hs
		1049455 M3K15_HUMAN (2-1278): 0: 1187: 43.56		1433F_HUMAN (2-240): 1.27e-107: 312: 74.49
+	Hs
		730852 M3K5_HUMAN (2-1282): 0: 1193: 44.32		1433S_HUMAN (1-237): 8.31e-104: 302: 71.97
+	Hs
		168666 CSKP_HUMAN (648-1288): 2.94e-132: 431: 16.57		1433E_HUMAN (2-241): 9.95e-144: 403: 68.18
+	Hs
		691170 MARK2_HUMAN (596-1261): 1.84e-129: 419: 15.28		1433T_HUMAN (1-245): 2.61e-140: 395: 79.59
+	Hs
		729991 MARK2_HUMAN (596-1261): 1.84e-129: 419: 15.28		1433B_HUMAN (1-242): 9.05e-140: 393: 87.60
+	Hs
		730714 MARK2_HUMAN (596-1261): 1.84e-129: 419: 15.28		1433S_HUMAN (1-237): 8.31e-104: 302: 71.97