Interactor 1: ABL (P00522)
Tyrosine-protein kinase Abl (EC 2.7.10.2) (D-ash) (Protein abelson)
Gene: ABL

Interactor 2: EGFR (P04412)
Epidermal growth factor receptor (Egfr) (EC 2.7.10.1) (Drosophila relative of ERBB) (Gurken receptor) (Protein torpedo)
Gene: EGFR

Species: Drosophila melanogaster

Source: biogrid

Category: Small-scale

Confidence: High

Method score Annotation score Interaction score
0.38 1.00 0.621

The method score is based on:

Property Details
Experiments 17637670
Identification Methods two hybrid
Interaction Type direct interaction

The annotation score is based on:

Property Details
Interacting Pfam domains PK_Tyr_Ser-Thr~PK_Tyr_Ser-Thr, PK_Tyr_Ser-Thr~SH2, PK_Tyr_Ser-Thr~SH3_1
Common GO terms GO:0005524 - ATP binding
GO:0007391 - dorsal closure
GO:0016318 - ommatidial rotation
GO:0048749 - compound eye development
Homologous interactions 20

Homologous interactions (Top 20)

Color coding for hit scores

1 1620
Dm

1 1426
+ Dm
+ Mm
+ Hs
+ Hs
+ Hs
+ Hs
+ Mm
+ Hs
+ Hs
+ Hs
+ Hs
+ Hs
+ Mm
+ Hs
+ Hs
+ Hs
+ Hs
+ Hs
+ Hs
+ Hs

Service provided by Combinatics, Japan

Last updated: 15 Jul 2024