HitPredict

Interactor 1: ABL1 (P00520)
Tyrosine-protein kinase ABL1 (EC 2.7.10.2) (Abelson murine leukemia viral oncogene homolog 1) (Abelson tyrosine-protein kinase 1) (Proto-oncogene c-Abl) (p150)
Gene: ABL1

Interactor 2: NCK1 (Q99M51)
SH2/SH3 adapter protein Nck1 (Cytoplasmic protein Nck1) (NCK adapter protein 1) (Nck-1)
Gene: NCK1

Species: Mus musculus

Source: intact

Category: Small-scale

Confidence: High

Method score Annotation score Interaction score
0.60 1.00 0.777

The method score is based on:

Property Details
Experiments 10967110, 15148308
Identification Methods pull down, anti tag coimmunoprecipitation
Interaction Type direct interaction, association, physical association

The annotation score is based on:

Property Details
Interacting Pfam domains PK_Tyr_Ser-Thr~SH2, PK_Tyr_Ser-Thr~SH3_1, SH2~SH2, SH2~SH3_1, SH3_1~SH3_1
Common GO terms GO:0005634 - nucleus
GO:0005829 - cytosol
GO:0019904 - protein domain specific binding
GO:0034976 - response to endoplasmic reticulum stress
GO:0046875 - ephrin receptor binding
Homologous interactions 20

Homologous interactions (Top 20)

Color coding for hit scores

1 1123
Mm

1 377
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Service provided by Combinatics, Japan

Last updated: 15 Jul 2024