Interactor 1: ABL1 (P00520)
Tyrosine-protein kinase ABL1 (EC 2.7.10.2) (Abelson murine leukemia viral oncogene homolog 1) (Abelson tyrosine-protein kinase 1) (Proto-oncogene c-Abl) (p150)
Gene: ABL1

Interactor 2: Q8C5V7 (Q8C5V7)
Rap guanine nucleotide exchange factor 1
Gene: Rapgef1

Species: Mus musculus

Source: biogrid

Category: Small-scale

Confidence: High

Method score Annotation score Interaction score
0.38 0.60 0.479

The method score is based on:

Property Details
Experiments 16443220
Identification Methods affinity chromatography technology
Interaction Type physical association

The annotation score is based on:

Property Details
Interacting Pfam domains -
Common GO terms GO:0032991 - protein-containing complex
GO:0048008 - platelet-derived growth factor receptor signaling pathway
GO:0048471 - perinuclear region of cytoplasm
GO:0070371 - ERK1 and ERK2 cascade
GO:0070373 - negative regulation of ERK1 and ERK2 cascade
and 2 others

more...

Homologous interactions 14

Homologous interactions

Color coding for hit scores

1 1123
Mm

1 642
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Last updated: 15 Jul 2024