Interactor 1: CDK1 (P00546)
Cyclin-dependent kinase 1 (CDK1) (EC 2.7.11.22) (Cell division control protein 28) (Cell division protein kinase 1)
Gene: CDC28
Interactor 2: CAK1 (P43568)
Serine/threonine-protein kinase CAK1 (EC 2.7.11.22) (CDK-activating kinase)
Gene: CAK1
Species: Saccharomyces cerevisiae S288C
Source: mint
Category: Small-scale
Confidence: High
| Method score | Annotation score | Interaction score |
|---|---|---|
| 0.95 | 1.00 | 0.976 |
The method score is based on:
| Property | Details |
|---|---|
| Experiments | 8752211, 10688190, 8336723, 17634282, 19647054, 10793138, 9393434, 8752210, 20489023, 14690591 |
| Identification Methods | coimmunoprecipitation, two hybrid, affinity chromatography technology, pull down, enzymatic study, anti tag coimmunoprecipitation, two hybrid array |
| Interaction Type | physical association, direct interaction, association |
The annotation score is based on:
| Property | Details |
|---|---|
| Interacting Pfam domains | Pkinase~Pkinase |
| Common GO terms | GO:0000086 - G2/M transition of mitotic cell cycle GO:0004674 - protein serine/threonine kinase activity GO:0004693 - cyclin-dependent protein serine/threonine kinase activity GO:0005524 - ATP binding GO:0005634 - nucleus and 2 others more... |
| Homologous interactions | 17 |
Homologous interactions
Color coding for hit scores 
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Service provided by Combinatics, Japan
Last updated: 15 Jul 2024
