HitPredict

Interactor 1: AKT1 (P31749)
RAC-alpha serine/threonine-protein kinase (EC 2.7.11.1) (Protein kinase B) (PKB) (Protein kinase B alpha) (PKB alpha) (Proto-oncogene c-Akt) (RAC-PK-alpha)
Gene: AKT1

Interactor 2: TCPG (P49368)
T-complex protein 1 subunit gamma (TCP-1-gamma) (CCT-gamma) (Chaperonin containing T-complex polypeptide 1 subunit 3) (hTRiC5)
Gene: CCT3

Species: Homo sapiens

Source: intact

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.54	0.60	0.571

Property	Details
Experiments	31980649, unassigned2173
Identification Methods	affinity chromatography technology, anti tag coimmunoprecipitation
Interaction Type	physical association, association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0005524 - ATP binding GO:0005829 - cytosol
Homologous interactions	18

Homologous interactions

Color coding for hit scores

	1 480 Hs			1 545
+	Hs
		681999 AKT1_HUMAN (1-480): 0: 586: 100.00		TCPH_HUMAN (2-536): 0: 574: 31.18
+	Hs
		681735 AKT1_HUMAN (1-480): 0: 586: 100.00		TCPE_HUMAN (4-530): 0: 559: 32.52
+	Hs
		573141 AKT1_HUMAN (1-480): 0: 586: 100.00		TCPA_HUMAN (10-533): 0: 549: 33.09
+	Hs
		826928 KS6B2_HUMAN (129-479): 4.6e-147: 430: 42.25		TCPG_HUMAN (1-545): 0: 640: 100.00
+	Hs
		826897 SGK2_HUMAN (122-475): 1.02e-147: 428: 47.75		TCPG_HUMAN (1-545): 0: 640: 100.00
+	Hs
		1306721 KS6B2_HUMAN (129-479): 4.6e-147: 430: 42.25		TCPH_HUMAN (2-536): 0: 574: 31.18
+	Hs
		1306691 SGK2_HUMAN (122-475): 1.02e-147: 428: 47.75		TCPH_HUMAN (2-536): 0: 574: 31.18
+	Hs
		821449 KS6B2_HUMAN (129-479): 4.6e-147: 430: 42.25		TCPE_HUMAN (4-530): 0: 559: 32.52
+	Hs
		821419 SGK2_HUMAN (122-475): 1.02e-147: 428: 47.75		TCPE_HUMAN (4-530): 0: 559: 32.52
+	Hs
		573515 KS6B2_HUMAN (129-479): 4.6e-147: 430: 42.25		TCPA_HUMAN (10-533): 0: 549: 33.09
+	Hs
		568585 KAPCA_HUMAN (138-445): 1.76e-144: 419: 42.53		TCPE_HUMAN (4-530): 0: 559: 32.52
+	Hs
		573486 SGK2_HUMAN (122-475): 1.02e-147: 428: 47.75		TCPA_HUMAN (10-533): 0: 549: 33.09
+	Hs
		681747 AKT1_HUMAN (1-480): 0: 586: 100.00		TCPD_HUMAN (16-524): 1.08e-90: 290: 34.56
+	Hs
		821353 SGK3_HUMAN (149-447): 5.26e-100: 310: 51.00		TCPE_HUMAN (4-530): 0: 559: 32.52
+	Hs
		843420 KS6B2_HUMAN (129-479): 4.6e-147: 430: 42.25		TCPD_HUMAN (16-524): 1.08e-90: 290: 34.56
+	Hs
		843394 SGK2_HUMAN (122-475): 1.02e-147: 428: 47.75		TCPD_HUMAN (16-524): 1.08e-90: 290: 34.56
+	Hs
		568593 KAPCA_HUMAN (138-445): 1.76e-144: 419: 42.53		TCPD_HUMAN (16-524): 1.08e-90: 290: 34.56
+	Hs
		843210 KS6A1_HUMAN (85-407): 6.15e-92: 296: 26.39		TCPD_HUMAN (16-524): 1.08e-90: 290: 34.56