HitPredict

Interactor 1: A0A0S2Z4Q8 (A0A0S2Z4Q8)
Protein phosphatase 1 regulatory subunit 12B isoform 2
Gene: PPP1R12B

Interactor 2: PP1B (P62140)
Serine/threonine-protein phosphatase PP1-beta catalytic subunit (PP-1B) (PPP1CD) (EC 3.1.3.16) (EC 3.1.3.53)
Gene: PPP1CB

Species: Homo sapiens

Source: intact

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.34	0.50	0.417

Property	Details
Experiments	26871637
Identification Methods	two hybrid array
Interaction Type	physical association

Property	Details
Interacting Pfam domains	-
Common GO terms	-
Homologous interactions	20

Homologous interactions (Top 20)

Color coding for hit scores

	1 184 Hs			1 327
+	Hs
		968289 ASPP2_HUMAN (9-166): 3.48e-41: 149: 32.08		PP1B_HUMAN (1-327): 0: 597: 100.00
+	Hs
		968266 Q05BL1_HUMAN (9-166): 6.22e-41: 148: 32.08		PP1B_HUMAN (1-327): 0: 597: 100.00
+	Hs
		239308 MYPT2_HUMAN (1-180): 8.1e-36: 134: 18.85		PP1B_HUMAN (1-327): 0: 597: 100.00
+	Mm
		98307 E9QJU8_MOUSE (11-166): 1.18e-41: 150: 33.12		PP1A_MOUSE (1-326): 0: 576: 88.49
+	Hs
		967717 ASPP2_HUMAN (9-166): 3.48e-41: 149: 32.08		PP1A_HUMAN (1-326): 0: 576: 88.79
+	Hs
		967682 Q05BL1_HUMAN (9-166): 6.22e-41: 148: 32.08		PP1A_HUMAN (1-326): 0: 576: 88.79
+	Hs
		786806 BARD1_HUMAN (55-183): 1.55e-42: 152: 34.62		PP1G_HUMAN (1-327): 0: 569: 86.89
+	Hs
		786595 ASPP2_HUMAN (9-166): 3.48e-41: 149: 32.08		PP1G_HUMAN (1-327): 0: 569: 86.89
+	Hs
		786558 Q05BL1_HUMAN (9-166): 6.22e-41: 148: 32.08		PP1G_HUMAN (1-327): 0: 569: 86.89
+	Hs
		968466 RAI14_HUMAN (48-179): 6.72e-31: 119: 20.30		PP1B_HUMAN (1-327): 0: 597: 100.00
+	Hs
		171217 MYPT1_HUMAN (15-175): 3.69e-30: 117: 19.82		PP1B_HUMAN (1-327): 0: 597: 100.00
+	Hs
		967671 ANK2_HUMAN (62-183): 2.08e-37: 138: 29.51		PP1A_HUMAN (1-326): 0: 576: 88.79
+	Gg
		969133 MYPT1_CHICK (1-175): 1.66e-29: 115: 19.50		PP1B_CHICK (1-327): 0: 597: 100.00
+	Hs
		239307 MYPT2_HUMAN (1-180): 8.1e-36: 134: 18.85		PP1A_HUMAN (1-326): 0: 576: 88.79
+	Mm
		968132 MYPT2_MOUSE (1-180): 5.12e-35: 131: 18.85		PP1A_MOUSE (1-326): 0: 576: 88.49
+	Hs
		239304 MYPT2_HUMAN (1-180): 8.1e-36: 134: 18.85		PP1G_HUMAN (1-327): 0: 569: 86.89
+	Hs
		171216 MYPT1_HUMAN (15-175): 3.69e-30: 117: 19.82		PP1A_HUMAN (1-326): 0: 576: 88.79
+	Hs
		786897 RAI14_HUMAN (48-179): 6.72e-31: 119: 20.30		PP1G_HUMAN (1-327): 0: 569: 86.89
+	Hs
		171191 MYPT1_HUMAN (15-175): 3.69e-30: 117: 19.82		PP1G_HUMAN (1-327): 0: 569: 86.89
+	Hs
		920423 DAPK1_HUMAN (12-183): 1.37e-45: 162: 23.73		PP2AA_HUMAN (8-303): 2.78e-176: 491: 45.79