Interactor 1: UROK (P00749)
Urokinase-type plasminogen activator (U-plasminogen activator) (uPA) (EC 3.4.21.73) [Cleaved into: Urokinase-type plasminogen activator long chain A; Urokinase-type plasminogen activator short chain A; Urokinase-type plasminogen activator chain B]
Gene: PLAU

Interactor 2: LRP2 (P98164)
Low-density lipoprotein receptor-related protein 2 (LRP-2) (Glycoprotein 330) (gp330) (Megalin)
Gene: LRP2

Species: Homo sapiens

Source: biogrid

Category: Small-scale

Confidence: High

Method score Annotation score Interaction score
0.41 1.00 0.647

The method score is based on:

Property Details
Experiments 8344937
Identification Methods pull down
Interaction Type direct interaction

The annotation score is based on:

Property Details
Interacting Pfam domains FXa_inhibition~Trypsin, Ldl_recept_a~Trypsin
Common GO terms GO:0005886 - plasma membrane
GO:0009897 - external side of plasma membrane
GO:0070062 - extracellular exosome
Homologous interactions 7

Homologous interactions

Color coding for hit scores

1 431
Hs

1 4655
+ Hs
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Service provided by Combinatics, Japan

Last updated: 15 Jul 2024