Protein: EYA1
Protein phosphatase EYA1 (EC 3.1.3.16) (EC 3.1.3.48) (Eyes absent homolog 1)

Gene: EYA1
Organism: Homo sapiens
Interactions: 46
UniProt ID: Q99502

Gene Ontology (top 5):
GO:0001656 - metanephros development
GO:0001658 - branching involved in ureteric bud morphogenesis
GO:0003151 - outflow tract morphogenesis
GO:0003723 - RNA binding
GO:0004722 - protein serine/threonine phosphatase activity

Download interactions: TXT   MITAB-2.5

Interaction Interactor Experiments Homologs Category Interaction
Score
Confidence

1149418

SIX1
Homeobox protein SIX1

6

20

Small-scale

0.952

High

1405003

SIX2
Homeobox protein SIX2

3

20

High-throughput

0.871

High

1323268

SIX5
Homeobox protein SIX5

1

20

High-throughput

0.691

High

1405004

SIX4
Homeobox protein SIX4

1

20

High-throughput

0.691

High

849032

PTN9
Tyrosine-protein phosphatase non-receptor type 9

2

2

High-throughput

0.628

High

1405006

CERT
Ceramide transfer protein

2

2

High-throughput

0.628

High

341657

EYA4
Protein phosphatase EYA4

1

18

High-throughput

0.618

High

591804

H2AX
Histone H2AX

2

8

Small-scale

0.611

High

1380111

FBXW7
F-box/WD repeat-containing protein 7

2

7

Small-scale

0.584

High

372935

MYC
Myc proto-oncogene protein

1

12

Small-scale

0.561

High

891759

GSK3B
Glycogen synthase kinase-3 beta

1

6

Small-scale

0.561

High

920223

PLK1
Serine/threonine-protein kinase PLK1

1

7

High-throughput

0.561

High

244004

JIP4
C-Jun-amino-terminal kinase-interacting protein 4

1

6

High-throughput

0.536

High

553051

PIP
Prolactin-inducible protein

1

1

High-throughput

0.536

High

589494

RFA2
Replication protein A 32 kDa subunit

1

8

High-throughput

0.536

High

696304

RFA1
Replication protein A 70 kDa DNA-binding subunit

1

5

High-throughput

0.536

High

768976

RFA3
Replication protein A 14 kDa subunit

1

6

High-throughput

0.536

High

1405002

GRPE1
GrpE protein homolog 1, mitochondrial

1

1

High-throughput

0.536

High

573638

ENPL
Endoplasmin

1

4

High-throughput

0.515

High

285715

BAF
Barrier-to-autointegration factor

1

0

High-throughput

0.513

High

928747

CACB3
Voltage-dependent L-type calcium channel subunit beta-3

1

1

High-throughput

0.489

High

1038030

CACB1
Voltage-dependent L-type calcium channel subunit beta-1

1

1

High-throughput

0.489

High

1123271

DPYL3
Dihydropyrimidinase-related protein 3

1

2

High-throughput

0.489

High

1405001

DNAI2
Dynein axonemal intermediate chain 2

1

14

High-throughput

0.489

High

425752

PERM
Myeloperoxidase

1

1

High-throughput

0.479

High

459733

PROF1
Profilin-1

1

3

High-throughput

0.479

High

553731

ANXA3
Annexin A3

1

1

High-throughput

0.479

High

568168

PLSL
Plastin-2

1

2

High-throughput

0.479

High

595571

H15
Histone H1.5

1

3

High-throughput

0.479

High

652568

NR4A1
Nuclear receptor subfamily 4immunitygroup A member 1

1

20

Small-scale

0.479

High

837804

LAP2B
Lamina-associated polypeptide 2, isoforms beta/gamma

1

1

High-throughput

0.479

High

1155694

EZH2
Histone-lysine N-methyltransferase EZH2

1

19

High-throughput

0.479

High

1405005

FZR1
Fizzy-related protein homolog

1

12

Small-scale

0.479

High

442454

GELS
Gelsolin

1

0

High-throughput

0.458

High

712262

TKT
Transketolase

1

0

High-throughput

0.458

High

1391016

OTUB1
Ubiquitin thioesterase OTUB1

1

0

Small-scale

0.458

High

837414

LAP2A
Lamina-associated polypeptide 2, isoform alpha

1

1

High-throughput

0.445

High

387314

APOA1
Apolipoprotein A-I

1

1

High-throughput

0.437

High

1358560

POF1B
Protein POF1B

1

1

High-throughput

0.437

High

637058

VATB2
V-type proton ATPase subunit B, brain isoform

1

0

High-throughput

0.279

Low

369387

A1AT
Alpha-1-antitrypsin

1

0

High-throughput

0.249

Low

369910

CO3
Complement C3

1

0

High-throughput

0.249

Low

390941

TRFE
Serotransferrin

1

0

High-throughput

0.249

Low

402405

GBA1
Lysosomal acid glucosylceramidase

1

0

High-throughput

0.249

Low

628642

CAP7
Azurocidin

1

0

High-throughput

0.249

Low

1294675

NDUAB
NADH dehydrogenase [ubiquinone] 1 alpha subcomplex subunit 11

1

0

High-throughput

0.249

Low


Service provided by Combinatics, Japan

Last updated: 11Aug2025