HitPredict

Interactor 1: EYA4 (O95677)
Protein phosphatase EYA4 (EC 3.1.3.48) (Eyes absent homolog 4)
Gene: EYA4

Interactor 2: NFIA (Q12857)
Nuclear factor 1 A-type (NF1-A) (Nuclear factor 1/A) (CCAAT-box-binding transcription factor) (CTF) (Nuclear factor I/A) (NF-I/A) (NFI-A) (TGGCA-binding protein)
Gene: NFIA

Species: Homo sapiens

Source: biogrid

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.38	0.60	0.479

Property	Details
Experiments	39617063
Identification Methods	proximity labelling technology
Interaction Type	physical association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0005634 - nucleus
Homologous interactions	20

Homologous interactions (Top 20)

Color coding for hit scores

	1 639 Hs			1 509
+	Hs
		341569 EYA4_HUMAN (1-639): 0: 652: 100.00		NFIX_HUMAN (1-508): 9.7e-154: 449: 67.32
+	Hs
		341507 EYA4_HUMAN (1-639): 0: 652: 100.00		NFIC_HUMAN (3-509): 2.95e-130: 390: 57.61
+	Hs
		142774 EYA4_HUMAN (1-639): 0: 652: 100.00		NFIB_HUMAN (1-413): 8.27e-127: 378: 61.41
+	Hs
		1087969 EYA3_HUMAN (89-639): 5.72e-168: 493: 53.12		NFIA_HUMAN (1-509): 1.11e-161: 470: 100.00
+	Hs
		1133626 EYA3_HUMAN (89-639): 5.72e-168: 493: 53.12		NFIX_HUMAN (1-508): 9.7e-154: 449: 67.32
+	Hs
		474233 EYA3_HUMAN (89-639): 5.72e-168: 493: 53.12		NFIC_HUMAN (3-509): 2.95e-130: 390: 57.61
+	Hs
		143211 EYA3_HUMAN (89-639): 5.72e-168: 493: 53.12		NFIB_HUMAN (1-413): 8.27e-127: 378: 61.41
+	Hs
		130343 EYA4_HUMAN (1-639): 0: 652: 100.00		SPT5H_HUMAN (181-357): 1.9e-09: 62.6: 15.76
+	Hs
		1087875 KMT2C_HUMAN (4-371): 1.1e-09: 64.2: 10.00		NFIA_HUMAN (1-509): 1.11e-161: 470: 100.00
+	Hs
		1133540 KMT2C_HUMAN (4-371): 1.1e-09: 64.2: 10.00		NFIX_HUMAN (1-508): 9.7e-154: 449: 67.32
+	Hs
		130356 SPT5H_HUMAN (2-176): 7.76e-10: 64.2: 13.07		NFIC_HUMAN (3-509): 2.95e-130: 390: 57.61
+	Hs
		474133 KMT2C_HUMAN (4-371): 1.1e-09: 64.2: 10.00		NFIC_HUMAN (3-509): 2.95e-130: 390: 57.61
+	Hs
		143124 KMT2C_HUMAN (4-371): 1.1e-09: 64.2: 10.00		NFIB_HUMAN (1-413): 8.27e-127: 378: 61.41
+	Hs
		925711 EWS_HUMAN (103-334): 1.19e-32: 135: 17.21		SC24C_HUMAN (232-508): 5.35e-13: 73.8: 10.56
+	Hs
		1033338 EWS_HUMAN (103-334): 1.19e-32: 135: 17.21		PCLO_HUMAN (224-506): 2.88e-11: 68.4: 13.64
+	Dm
		402272 ENC_DROME (40-402): 2.09e-29: 127: 17.62		RPB1_DROME (180-504): 1.51e-10: 66.1: 13.81
+	Hs
		323852 SC24C_HUMAN (18-362): 7.52e-12: 70.8: 10.48		SC31A_HUMAN (222-499): 9.06e-21: 98.4: 12.06
+	Mm
		1455913 PCLO_MOUSE (3-364): 1.55e-10: 66.9: 11.52		PCLO_MOUSE (187-508): 2.68e-12: 71.9: 11.66
+	Dm
		119660 M9PB30_DROME (6-266): 8.68e-11: 67.7: 11.64		M9PB30_DROME (182-505): 9.65e-09: 60.3: 12.39
+	Hs
		130548 ARI1B_HUMAN (89-361): 5.82e-09: 61.5: 12.41		SPT5H_HUMAN (181-357): 1.9e-09: 62.6: 15.76