HitPredict

Interactor 1: MYC (P01106)
Myc proto-oncogene protein (Class E basic helix-loop-helix protein 39) (bHLHe39) (Proto-oncogene c-Myc) (Transcription factor p64)
Gene: MYC

Interactor 2: MCM3 (P25205)
DNA replication licensing factor MCM3 (EC 3.6.4.12) (DNA polymerase alpha holoenzyme-associated protein P1) (P1-MCM3) (RLF subunit beta) (p102)
Gene: MCM3

Species: Homo sapiens

Source: intact

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.68	0.60	0.640

Property	Details
Experiments	29467282, 36424410, 17353931
Identification Methods	affinity chromatography technology, proximity labelling technology, anti bait coimmunoprecipitation
Interaction Type	physical association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0003677 - DNA binding GO:0005634 - nucleus GO:0005654 - nucleoplasm
Homologous interactions	7

Homologous interactions

Color coding for hit scores

	1 454 Hs			1 808
+	Hs
		379028 MYCN_HUMAN (12-451): 9.39e-59: 201: 33.40		MCM3_HUMAN (1-808): 0: 944: 100.00
+	Hs
		346235 MYC_HUMAN (1-454): 1.73e-122: 366: 100.00		MCM2_HUMAN (10-721): 0: 707: 30.62
+	Hs
		346783 MYC_HUMAN (1-454): 1.73e-122: 366: 100.00		MCM6_HUMAN (2-800): 0: 688: 26.50
+	Hs
		346066 MYC_HUMAN (1-454): 1.73e-122: 366: 100.00		MCM5_HUMAN (9-713): 0: 685: 28.92
+	Hs
		346065 MYC_HUMAN (1-454): 1.73e-122: 366: 100.00		MCM4_HUMAN (9-739): 0: 661: 28.03
+	Hs
		346067 MYC_HUMAN (1-454): 1.73e-122: 366: 100.00		MCM7_HUMAN (10-669): 0: 650: 31.62
+	Hs
		379063 MYCN_HUMAN (12-451): 9.39e-59: 201: 33.40		MCM7_HUMAN (10-669): 0: 650: 31.62