HitPredict

Interactor 1: MYC (P01106)
Myc proto-oncogene protein (Class E basic helix-loop-helix protein 39) (bHLHe39) (Proto-oncogene c-Myc) (Transcription factor p64)
Gene: MYC

Interactor 2: EIF3B (P55884)
Eukaryotic translation initiation factor 3 subunit B (eIF3b) (Eukaryotic translation initiation factor 3 subunit 9) (Prt1 homolog) (hPrt1) (eIF-3-eta) (eIF3 p110) (eIF3 p116)
Gene: EIF3B

Species: Homo sapiens

Source: biogrid

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.56	0.50	0.533

Property	Details
Experiments	29467282, 35013218
Identification Methods	affinity chromatography technology
Interaction Type	physical association

Property	Details
Interacting Pfam domains	-
Common GO terms	-
Homologous interactions	13

Homologous interactions

Color coding for hit scores

	1 454 Hs			1 814
+	Hs
		347807 MYC_HUMAN (1-454): 1.73e-122: 366: 100.00		EIF2A_HUMAN (329-769): 3.23e-74: 255: 19.50
+	Hs
		348035 MYC_HUMAN (1-454): 1.73e-122: 366: 100.00		NLE1_HUMAN (507-723): 2.49e-34: 139: 17.03
+	Hs
		346404 MYC_HUMAN (1-454): 1.73e-122: 366: 100.00		WDR5_HUMAN (554-729): 7.19e-35: 137: 12.71
+	Hs
		346159 MYC_HUMAN (1-454): 1.73e-122: 366: 100.00		LIS1_HUMAN (231-410): 5.42e-23: 104: 10.73
+	Hs
		379821 MYCN_HUMAN (12-451): 9.39e-59: 201: 33.40		EIF2A_HUMAN (329-769): 3.23e-74: 255: 19.50
+	Hs
		267729 MYC_HUMAN (1-454): 1.73e-122: 366: 100.00		TAF5L_HUMAN (343-501): 2.2e-12: 72.5: 19.63
+	Hs
		379200 MYCN_HUMAN (12-451): 9.39e-59: 201: 33.40		WDR5_HUMAN (554-729): 7.19e-35: 137: 12.71
+	Hs
		607803 USF1_HUMAN (175-453): 1.02e-39: 146: 18.40		WDR5_HUMAN (554-729): 7.19e-35: 137: 12.71
+	Hs
		903353 MGAP_HUMAN (151-449): 1.22e-27: 118: 17.71		WDR5_HUMAN (554-729): 7.19e-35: 137: 12.71
+	Mm
		659344 MAX_MOUSE (354-454): 3.52e-25: 102: 32.67		WDR5_MOUSE (554-729): 7.19e-35: 137: 12.71
+	Hs
		898091 MAX_HUMAN (354-454): 1.39e-24: 101: 32.67		WDR5_HUMAN (554-729): 7.19e-35: 137: 12.71
+	Hs
		267736 MYCL_HUMAN (29-449): 4.2e-42: 154: 30.11		TAF5L_HUMAN (343-501): 2.2e-12: 72.5: 19.63
+	Hs
		267750 MAX_HUMAN (354-454): 1.39e-24: 101: 32.67		TAF5L_HUMAN (343-501): 2.2e-12: 72.5: 19.63