HitPredict

Interactor 1: MYC (P01106)
Myc proto-oncogene protein (Class E basic helix-loop-helix protein 39) (bHLHe39) (Proto-oncogene c-Myc) (Transcription factor p64)
Gene: MYC

Interactor 2: PHLB2 (Q86SQ0)
Pleckstrin homology-like domain family B member 2 (Protein LL5-beta)
Gene: PHLDB2

Species: Homo sapiens

Source: intact

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.62	0.50	0.558

Property	Details
Experiments	29467282, 21150319
Identification Methods	affinity chromatography technology, tandem affinity purification
Interaction Type	physical association, association

Property	Details
Interacting Pfam domains	-
Common GO terms	-
Homologous interactions	13

Homologous interactions

Color coding for hit scores

	1 454 Hs			1 1253
+	Hs
		347207 MYC_HUMAN (1-454): 1.73e-122: 366: 100.00		PHLB1_HUMAN (21-1252): 1.6e-69: 258: 28.61
+	Hs
		346088 MYC_HUMAN (1-454): 1.73e-122: 366: 100.00		MYH9_HUMAN (242-1165): 8.89e-36: 150: 10.57
+	Hs
		346097 MYC_HUMAN (1-454): 1.73e-122: 366: 100.00		MYH11_HUMAN (486-1136): 4.39e-23: 109: 11.38
+	Hs
		346089 MYC_HUMAN (1-454): 1.73e-122: 366: 100.00		MYH10_HUMAN (164-906): 2.35e-20: 100: 9.92
+	Hs
		347061 MYC_HUMAN (1-454): 1.73e-122: 366: 100.00		PHLB3_HUMAN (507-808): 8.68e-13: 74.7: 22.33
+	Hs
		346834 MYC_HUMAN (1-454): 1.73e-122: 366: 100.00		PLEC_HUMAN (379-991): 1.99e-10: 67.8: 12.17
+	Hs
		345843 MYC_HUMAN (1-454): 1.73e-122: 366: 100.00		DESP_HUMAN (412-840): 2.66e-10: 67.3: 19.03
+	Hs
		346766 MYC_HUMAN (1-454): 1.73e-122: 366: 100.00		DCTN1_HUMAN (447-912): 5.75e-10: 66.1: 15.78
+	Hs
		347016 MYC_HUMAN (1-454): 1.73e-122: 366: 100.00		CROCC_HUMAN (194-753): 1.04e-09: 65.5: 9.46
+	Hs
		379070 MYCN_HUMAN (12-451): 9.39e-59: 201: 33.40		MYH9_HUMAN (242-1165): 8.89e-36: 150: 10.57
+	Hs
		379071 MYCN_HUMAN (12-451): 9.39e-59: 201: 33.40		MYH10_HUMAN (164-906): 2.35e-20: 100: 9.92
+	Hs
		378986 MYCN_HUMAN (12-451): 9.39e-59: 201: 33.40		DESP_HUMAN (412-840): 2.66e-10: 67.3: 19.03
+	Hs
		898141 MAX_HUMAN (354-454): 1.39e-24: 101: 32.67		PHLB3_HUMAN (507-808): 8.68e-13: 74.7: 22.33