HitPredict

Interactor 1: RASN (P01111)
GTPase NRas (EC 3.6.5.2) (Transforming protein N-Ras)
Gene: NRAS

Interactor 2: TANC1 (Q9C0D5)
Protein TANC1 (Tetratricopeptide repeat, ankyrin repeat and coiled-coil domain-containing protein 1)
Gene: TANC1

Species: Homo sapiens

Source: biogrid

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.38	0.80	0.553

Property	Details
Experiments	30639242
Identification Methods	proximity labelling technology
Interaction Type	physical association

Property	Details
Interacting Pfam domains	Ank~Ras, Ank_2~Ras, Ank_4~Ras
Common GO terms	-
Homologous interactions	17

Homologous interactions

Color coding for hit scores

	1 189 Hs			1 1861
+	Hs
		350525 RASK_HUMAN (16-189): 7.56e-85: 249: 85.71		TANC1_HUMAN (1-1861): 0: 1674: 100.00
+	Hs
		1070386 RAB35_HUMAN (4-171): 6.96e-84: 247: 34.71		TANC1_HUMAN (1-1861): 0: 1674: 100.00
+	Hs
		350675 RASK_HUMAN (16-189): 7.56e-85: 249: 85.71		ANR50_HUMAN (385-1762): 0: 692: 21.25
+	Hs
		349001 RASN_HUMAN (1-189): 9.9e-80: 236: 100.00		ANR50_HUMAN (385-1762): 0: 692: 21.25
+	Hs
		350123 RASK_HUMAN (16-189): 7.56e-85: 249: 85.71		ANK3_HUMAN (758-1857): 3.69e-163: 558: 13.95
+	Hs
		1021405 RAB35_HUMAN (4-171): 6.96e-84: 247: 34.71		ANK3_HUMAN (758-1857): 3.69e-163: 558: 13.95
+	Dm
		65552 RALA_DROME (4-169): 1.5e-59: 186: 52.70		A8JNM5_DROME (743-1857): 3.99e-171: 583: 15.51
+	Dm
		1248518 Q962I2_DROME (4-170): 1.83e-59: 186: 51.79		Q8SWY2_DROME (699-1478): 1.09e-140: 466: 18.01
+	Hs
		350083 RASK_HUMAN (16-189): 7.56e-85: 249: 85.71		ANK2_HUMAN (832-1445): 1.76e-99: 360: 19.88
+	Hs
		349253 RASH_HUMAN (1-188): 8.6e-78: 232: 85.64		ANK2_HUMAN (832-1445): 1.76e-99: 360: 19.88
+	Hs
		350674 RASK_HUMAN (16-189): 7.56e-85: 249: 85.71		KDIS_HUMAN (1153-1294): 5.61e-31: 136: 26.67
+	Hs
		1070450 RAB35_HUMAN (4-171): 6.96e-84: 247: 34.71		KDIS_HUMAN (1153-1294): 5.61e-31: 136: 26.67
+	Hs
		349000 RASN_HUMAN (1-189): 9.9e-80: 236: 100.00		KDIS_HUMAN (1153-1294): 5.61e-31: 136: 26.67
+	Hs
		914450 RB11A_HUMAN (4-184): 1.5e-74: 224: 33.88		KDIS_HUMAN (1153-1294): 5.61e-31: 136: 26.67
+	Hs
		895318 RAB2A_HUMAN (4-185): 1.53e-73: 222: 31.52		KDIS_HUMAN (1153-1294): 5.61e-31: 136: 26.67
+	Hs
		349212 RASH_HUMAN (1-188): 8.6e-78: 232: 85.64		DAPK1_HUMAN (1137-1270): 4.08e-10: 67.4: 32.09
+	Hs
		862018 RB11A_HUMAN (4-184): 1.5e-74: 224: 33.88		DAPK1_HUMAN (1137-1270): 4.08e-10: 67.4: 32.09