HitPredict

Interactor 1: LATS1 (O95835)
Serine/threonine-protein kinase LATS1 (EC 2.7.11.1) (Large tumor suppressor homolog 1) (WARTS protein kinase) (h-warts)
Gene: LATS1

Interactor 2: MYH7 (P12883)
Myosin-7 (Myosin heavy chain 7) (Myosin heavy chain slow isoform) (MyHC-slow) (Myosin heavy chain, cardiac muscle beta isoform) (MyHC-beta)
Gene: MYH7

Species: Homo sapiens

Source: intact

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.47	0.60	0.536

Property	Details
Experiments	33961781
Identification Methods	affinity chromatography technology, anti tag coimmunoprecipitation
Interaction Type	physical association, association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0005524 - ATP binding GO:0005737 - cytoplasm
Homologous interactions	16

Homologous interactions

Color coding for hit scores

	1 1130 Hs			1 1935
+	Hs
		348954 LATS1_HUMAN (1-1130): 0: 925: 100.00		MYH6_HUMAN (1-1932): 0: 1149: 92.66
+	Hs
		348951 LATS1_HUMAN (1-1130): 0: 925: 100.00		MYH1_HUMAN (2-1935): 0: 1146: 81.00
+	Hs
		349307 LATS1_HUMAN (1-1130): 0: 925: 100.00		MYH4_HUMAN (2-1935): 0: 1143: 80.64
+	Hs
		349287 LATS1_HUMAN (1-1130): 0: 925: 100.00		MYH2_HUMAN (2-1935): 0: 1132: 80.82
+	Hs
		349288 LATS1_HUMAN (1-1130): 0: 925: 100.00		MYH13_HUMAN (2-1934): 0: 1128: 76.91
+	Hs
		562995 KAPCB_HUMAN (661-1055): 6.64e-133: 409: 31.58		MYH6_HUMAN (1-1932): 0: 1149: 92.66
+	Hs
		556840 KAPCB_HUMAN (661-1055): 6.64e-133: 409: 31.58		MYH1_HUMAN (2-1935): 0: 1146: 81.00
+	Hs
		651743 KAPCB_HUMAN (661-1055): 6.64e-133: 409: 31.58		MYH4_HUMAN (2-1935): 0: 1143: 80.64
+	Hs
		651734 KAPCB_HUMAN (661-1055): 6.64e-133: 409: 31.58		MYH2_HUMAN (2-1935): 0: 1132: 80.82
+	Hs
		348955 LATS1_HUMAN (1-1130): 0: 925: 100.00		MYH8_HUMAN (751-1848): 3.49e-57: 222: 16.20
+	Hs
		348948 LATS1_HUMAN (1-1130): 0: 925: 100.00		MYH3_HUMAN (716-1348): 6.07e-26: 119: 14.65
+	Hs
		773091 ST38L_HUMAN (627-1089): 1.01e-161: 489: 40.82		MYH9_HUMAN (1075-1934): 9.06e-49: 194: 15.81
+	Hs
		605578 KAPCA_HUMAN (661-1058): 1.57e-137: 421: 31.59		MYH10_HUMAN (981-1935): 1.56e-62: 239: 18.48
+	Hs
		728066 AKT1_HUMAN (595-1079): 1.92e-140: 434: 24.60		MYH9_HUMAN (1075-1934): 9.06e-49: 194: 15.81
+	Hs
		605577 KAPCA_HUMAN (661-1058): 1.57e-137: 421: 31.59		MYH9_HUMAN (1075-1934): 9.06e-49: 194: 15.81
+	Hs
		772782 ROCK1_HUMAN (694-1046): 9.27e-66: 245: 39.94		MYH9_HUMAN (1075-1934): 9.06e-49: 194: 15.81