HitPredict

Interactor 1: RASN (P01111)
GTPase NRas (EC 3.6.5.2) (Transforming protein N-Ras)
Gene: NRAS

Interactor 2: TB22B (Q9NU19)
TBC1 domain family member 22B
Gene: TBC1D22B

Species: Homo sapiens

Source: biogrid

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.38	0.80	0.553

Property	Details
Experiments	30639242
Identification Methods	proximity labelling technology
Interaction Type	physical association

Property	Details
Interacting Pfam domains	RabGAP-TBC~Ras
Common GO terms	-
Homologous interactions	20

Homologous interactions (Top 20)

Color coding for hit scores

	1 189 Hs			1 505
+	Hs
		914391 RB11A_HUMAN (4-184): 1.5e-74: 224: 33.88		TB22B_HUMAN (1-505): 9.73e-165: 477: 100.00
+	Hs
		350213 RASK_HUMAN (16-189): 7.56e-85: 249: 85.71		TB10B_HUMAN (18-502): 2.38e-83: 276: 15.22
+	Hs
		1070219 RAB35_HUMAN (4-171): 6.96e-84: 247: 34.71		TB10B_HUMAN (18-502): 2.38e-83: 276: 15.22
+	Hs
		894747 RAB8A_HUMAN (4-185): 2.24e-84: 249: 36.02		TBC9B_HUMAN (50-502): 2.33e-78: 268: 15.15
+	Hs
		894727 RAB8A_HUMAN (4-185): 2.24e-84: 249: 36.02		TBC8B_HUMAN (49-480): 1.24e-77: 265: 14.64
+	Hs
		894778 RAB8A_HUMAN (4-185): 2.24e-84: 249: 36.02		TBC15_HUMAN (123-496): 8.36e-80: 264: 20.41
+	Os
		1130875 Q84TA8_ORYSJ (4-183): 7.24e-75: 225: 34.97		Q5SMT0_ORYSJ (12-489): 2.28e-88: 286: 19.64
+	Hs
		232698 RAB2B_HUMAN (4-185): 2.66e-77: 231: 32.61		TBCD4_HUMAN (7-504): 2.2e-82: 280: 14.04
+	Hs
		349367 RASH_HUMAN (1-188): 8.6e-78: 232: 85.64		TB10B_HUMAN (18-502): 2.38e-83: 276: 15.22
+	Hs
		350278 RASK_HUMAN (16-189): 7.56e-85: 249: 85.71		TBCD9_HUMAN (51-494): 2.5e-74: 257: 13.26
+	Hs
		914176 RB11A_HUMAN (4-184): 1.5e-74: 224: 33.88		TBCD1_HUMAN (28-504): 5.48e-80: 272: 14.29
+	Hs
		1070473 RAB35_HUMAN (4-171): 6.96e-84: 247: 34.71		RBGP1_HUMAN (104-493): 4.58e-71: 246: 19.85
+	Hs
		894809 RAB8A_HUMAN (4-185): 2.24e-84: 249: 36.02		TBC17_HUMAN (78-500): 2.95e-72: 243: 18.95
+	Hs
		350412 RASK_HUMAN (16-189): 7.56e-85: 249: 85.71		TBCD5_HUMAN (130-499): 5.89e-70: 240: 17.37
+	Hs
		350509 RASK_HUMAN (16-189): 7.56e-85: 249: 85.71		TB10A_HUMAN (114-504): 7.31e-70: 233: 15.23
+	Hs
		348834 RASN_HUMAN (1-189): 9.9e-80: 236: 100.00		TBCD5_HUMAN (130-499): 5.89e-70: 240: 17.37
+	Hs
		918951 RAB1A_HUMAN (4-187): 1.35e-76: 229: 33.33		TBC17_HUMAN (78-500): 2.95e-72: 243: 18.95
+	Hs
		234370 RB11A_HUMAN (4-184): 1.5e-74: 224: 33.88		EVI5_HUMAN (51-503): 3.93e-72: 246: 13.79
+	Hs
		349612 RASH_HUMAN (1-188): 8.6e-78: 232: 85.64		TB10A_HUMAN (114-504): 7.31e-70: 233: 15.23
+	Hs
		914259 RB11A_HUMAN (4-184): 1.5e-74: 224: 33.88		TBCD5_HUMAN (130-499): 5.89e-70: 240: 17.37