HitPredict

Interactor 1: RASH (P01112)
GTPase HRas (EC 3.6.5.2) (H-Ras-1) (Ha-Ras) (Transforming protein p21) (c-H-ras) (p21ras) [Cleaved into: GTPase HRas, N-terminally processed]
Gene: HRAS

Interactor 2: EPB41 (P11171)
Protein 4.1 (P4.1) (4.1R) (Band 4.1) (EPB4.1) (Erythrocyte membrane protein band 4.1)
Gene: EPB41

Species: Homo sapiens

Source: biogrid

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.56	1.00	0.754

Property	Details
Experiments	30442766, 30639242
Identification Methods	proximity labelling technology
Interaction Type	physical association

Property	Details
Interacting Pfam domains	FERM_M~Ras
Common GO terms	GO:0005829 - cytosol GO:0005886 - plasma membrane
Homologous interactions	20

Homologous interactions (Top 20)

Color coding for hit scores

	1 189 Hs			1 864
+	Hs
		348485 RASN_HUMAN (1-188): 6.47e-88: 257: 85.64		EPB41_HUMAN (1-864): 0: 781: 100.00
+	Hs
		349830 RASK_HUMAN (1-188): 2.04e-84: 248: 86.24		EPB41_HUMAN (1-864): 0: 781: 100.00
+	Hs
		505614 RB11A_HUMAN (4-178): 4.48e-74: 223: 33.90		EPB41_HUMAN (1-864): 0: 781: 100.00
+	Hs
		348937 RASN_HUMAN (1-188): 6.47e-88: 257: 85.64		E41L5_HUMAN (166-858): 2.25e-170: 513: 26.50
+	Hs
		350574 RASK_HUMAN (1-188): 2.04e-84: 248: 86.24		E41L5_HUMAN (166-858): 2.25e-170: 513: 26.50
+	Hs
		348923 RASN_HUMAN (1-188): 6.47e-88: 257: 85.64		E41L1_HUMAN (137-864): 2.16e-161: 494: 41.50
+	Hs
		350550 RASK_HUMAN (1-188): 2.04e-84: 248: 86.24		E41L1_HUMAN (137-864): 2.16e-161: 494: 41.50
+	Hs
		914356 RB11A_HUMAN (4-178): 4.48e-74: 223: 33.90		E41L1_HUMAN (137-864): 2.16e-161: 494: 41.50
+	Hs
		350544 RASK_HUMAN (1-188): 2.04e-84: 248: 86.24		E41LB_HUMAN (210-838): 6.88e-143: 447: 27.57
+	Hs
		299225 RASN_HUMAN (1-188): 6.47e-88: 257: 85.64		FARP2_HUMAN (167-772): 3.94e-134: 428: 27.14
+	Hs
		299226 RASK_HUMAN (1-188): 2.04e-84: 248: 86.24		FARP2_HUMAN (167-772): 3.94e-134: 428: 27.14
+	Hs
		348745 RASN_HUMAN (1-188): 6.47e-88: 257: 85.64		FRMD7_HUMAN (210-805): 9.82e-128: 402: 26.07
+	Hs
		349026 RASN_HUMAN (1-188): 6.47e-88: 257: 85.64		FARP1_HUMAN (168-772): 1.31e-123: 400: 27.71
+	Hs
		350721 RASK_HUMAN (1-188): 2.04e-84: 248: 86.24		FARP1_HUMAN (168-772): 1.31e-123: 400: 27.71
+	Hs
		348539 RASN_HUMAN (1-188): 6.47e-88: 257: 85.64		MERL_HUMAN (195-763): 8.67e-121: 380: 19.69
+	Hs
		349925 RASK_HUMAN (1-188): 2.04e-84: 248: 86.24		MERL_HUMAN (195-763): 8.67e-121: 380: 19.69
+	Hs
		204587 RASN_HUMAN (1-188): 6.47e-88: 257: 85.64		E41L2_HUMAN (506-864): 1.22e-27: 122: 34.44
+	Hs
		204589 RASK_HUMAN (1-188): 2.04e-84: 248: 86.24		E41L2_HUMAN (506-864): 1.22e-27: 122: 34.44
+	Hs
		349019 RASN_HUMAN (1-188): 6.47e-88: 257: 85.64		E41L3_HUMAN (596-833): 2.3e-10: 66.5: 21.67
+	Hs
		350708 RASK_HUMAN (1-188): 2.04e-84: 248: 86.24		E41L3_HUMAN (596-833): 2.3e-10: 66.5: 21.67