HitPredict

Interactor 1: RASH (P01112)
GTPase HRas (EC 3.6.5.2) (H-Ras-1) (Ha-Ras) (Transforming protein p21) (c-H-ras) (p21ras) [Cleaved into: GTPase HRas, N-terminally processed]
Gene: HRAS

Interactor 2: EFNB1 (P98172)
Ephrin-B1 (EFL-3) (ELK ligand) (ELK-L) (EPH-related receptor tyrosine kinase ligand 2) (LERK-2) [Cleaved into: Ephrin-B1 C-terminal fragment (Ephrin-B1 CTF); Ephrin-B1 intracellular domain (Ephrin-B1 ICD)]
Gene: EFNB1

Species: Homo sapiens

Source: biogrid

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.56	0.60	0.584

Property	Details
Experiments	30639242, 30194290
Identification Methods	proximity labelling technology
Interaction Type	physical association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0005737 - cytoplasm GO:0005886 - plasma membrane GO:0098978 - glutamatergic synapse
Homologous interactions	10

Homologous interactions

Color coding for hit scores

	1 189 Hs			1 346
+	Hs
		348613 RASN_HUMAN (1-188): 6.47e-88: 257: 85.64		EFNB1_HUMAN (1-346): 0: 538: 100.00
+	Hs
		350074 RASK_HUMAN (1-188): 2.04e-84: 248: 86.24		EFNB1_HUMAN (1-346): 0: 538: 100.00
+	Hs
		914008 RB11A_HUMAN (4-178): 4.48e-74: 223: 33.90		EFNB1_HUMAN (1-346): 0: 538: 100.00
+	Hs
		348589 RASN_HUMAN (1-188): 6.47e-88: 257: 85.64		EFNB2_HUMAN (8-346): 1.88e-155: 441: 55.39
+	Hs
		349998 RASK_HUMAN (1-188): 2.04e-84: 248: 86.24		EFNB2_HUMAN (8-346): 1.88e-155: 441: 55.39
+	Hs
		856521 RB11A_HUMAN (4-178): 4.48e-74: 223: 33.90		EFNB2_HUMAN (8-346): 1.88e-155: 441: 55.39
+	Hs
		349211 RASH_HUMAN (16-189): 5.68e-73: 219: 100.00		EFNB2_HUMAN (8-346): 1.88e-155: 441: 55.39
+	Hs
		348679 RASN_HUMAN (1-188): 6.47e-88: 257: 85.64		EFNB3_HUMAN (33-346): 6.4e-107: 318: 41.28
+	Hs
		350194 RASK_HUMAN (1-188): 2.04e-84: 248: 86.24		EFNB3_HUMAN (33-346): 6.4e-107: 318: 41.28
+	Hs
		349340 RASH_HUMAN (16-189): 5.68e-73: 219: 100.00		EFNB3_HUMAN (33-346): 6.4e-107: 318: 41.28