HitPredict

Interactor 1: RASK (P01116)
GTPase KRas (EC 3.6.5.2) (K-Ras 2) (Ki-Ras) (c-K-ras) (c-Ki-ras) [Cleaved into: GTPase KRas, N-terminally processed]
Gene: KRAS

Interactor 2: 1433Z (P63104)
14-3-3 protein zeta/delta (Protein kinase C inhibitor protein 1) (KCIP-1)
Gene: YWHAZ

Species: Homo sapiens

Source: intact

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.71	0.60	0.656

Property	Details
Experiments	27684187, 34079125, 35271311
Identification Methods	affinity chromatography technology, proximity labelling technology, anti tag coimmunoprecipitation
Interaction Type	physical association, association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0005737 - cytoplasm GO:0005829 - cytosol GO:0005925 - focal adhesion
Homologous interactions	8

Homologous interactions

Color coding for hit scores

	1 189 Hs			1 245
+	Hs
		350028 RASK_HUMAN (1-189): 8.4e-77: 229: 100.00		1433E_HUMAN (2-241): 9.9e-144: 403: 68.18
+	Hs
		349892 RASK_HUMAN (1-189): 8.4e-77: 229: 100.00		1433T_HUMAN (1-245): 2.6e-140: 395: 79.59
+	Hs
		349918 RASK_HUMAN (1-189): 8.4e-77: 229: 100.00		1433B_HUMAN (1-242): 9.01e-140: 393: 87.60
+	Hs
		919617 RAP1A_HUMAN (1-165): 7.83e-63: 194: 58.08		1433Z_HUMAN (1-245): 1.67e-144: 405: 100.00
+	Hs
		350025 RASK_HUMAN (1-189): 8.4e-77: 229: 100.00		1433G_HUMAN (1-240): 2.37e-108: 314: 74.59
+	Hs
		350100 RASK_HUMAN (1-189): 8.4e-77: 229: 100.00		1433F_HUMAN (2-240): 1.26e-107: 312: 74.49
+	Hs
		904422 RB11A_HUMAN (4-184): 2.43e-72: 219: 33.88		1433G_HUMAN (1-240): 2.37e-108: 314: 74.59
+	Hs
		349919 RASK_HUMAN (1-189): 8.4e-77: 229: 100.00		1433S_HUMAN (1-237): 8.27e-104: 302: 71.97