HitPredict

Interactor 1: RASK (P01116)
GTPase KRas (EC 3.6.5.2) (K-Ras 2) (Ki-Ras) (c-K-ras) (c-Ki-ras) [Cleaved into: GTPase KRas, N-terminally processed]
Gene: KRAS

Interactor 2: ROR2 (Q01974)
Tyrosine-protein kinase transmembrane receptor ROR2 (EC 2.7.10.1) (Neurotrophic tyrosine kinase, receptor-related 2)
Gene: ROR2

Species: Homo sapiens

Source: biogrid

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.56	0.60	0.584

Property	Details
Experiments	30442766, 34079125
Identification Methods	proximity labelling technology
Interaction Type	physical association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0005886 - plasma membrane
Homologous interactions	20

Homologous interactions (Top 20)

Color coding for hit scores

	1 189 Hs			1 943
+	Hs
		349258 RASH_HUMAN (1-188): 6.53e-87: 255: 86.77		ROR2_HUMAN (1-943): 0: 840: 100.00
+	Hs
		348624 RASN_HUMAN (1-189): 2.37e-85: 251: 85.19		ROR2_HUMAN (1-943): 0: 840: 100.00
+	Hs
		968380 RAB35_HUMAN (4-187): 1.09e-82: 244: 31.28		ROR2_HUMAN (1-943): 0: 840: 100.00
+	Hs
		349257 RASH_HUMAN (1-188): 6.53e-87: 255: 86.77		ROR1_HUMAN (41-942): 0: 678: 56.94
+	Hs
		348623 RASN_HUMAN (1-189): 2.37e-85: 251: 85.19		ROR1_HUMAN (41-942): 0: 678: 56.94
+	Hs
		350088 RASK_HUMAN (1-189): 8.4e-77: 229: 100.00		ROR1_HUMAN (41-942): 0: 678: 56.94
+	Hs
		349286 RASH_HUMAN (1-188): 6.53e-87: 255: 86.77		PTK7_HUMAN (7-746): 1.62e-145: 461: 22.50
+	Hs
		348643 RASN_HUMAN (1-189): 2.37e-85: 251: 85.19		PTK7_HUMAN (7-746): 1.62e-145: 461: 22.50
+	Hs
		350138 RASK_HUMAN (1-189): 8.4e-77: 229: 100.00		PTK7_HUMAN (7-746): 1.62e-145: 461: 22.50
+	Hs
		349346 RASH_HUMAN (1-188): 6.53e-87: 255: 86.77		NTRK3_HUMAN (259-755): 4.11e-127: 406: 28.91
+	Hs
		349222 RASH_HUMAN (1-188): 6.53e-87: 255: 86.77		EPHA4_HUMAN (370-779): 6.97e-110: 364: 33.01
+	Rn
		589761 RASH_RAT (1-188): 6.53e-87: 255: 86.77		NTRK1_RAT (393-749): 1.42e-110: 361: 36.70
+	Hs
		350003 RASK_HUMAN (1-189): 8.4e-77: 229: 100.00		EPHA4_HUMAN (370-779): 6.97e-110: 364: 33.01
+	Hs
		349065 RASH_HUMAN (1-188): 6.53e-87: 255: 86.77		INSR_HUMAN (467-747): 2.53e-53: 204: 39.15
+	Hs
		348472 RASN_HUMAN (1-189): 2.37e-85: 251: 85.19		INSR_HUMAN (467-747): 2.53e-53: 204: 39.15
+	Hs
		665604 RAB35_HUMAN (4-187): 1.09e-82: 244: 31.28		EPHB2_HUMAN (466-746): 4.25e-53: 203: 40.70
+	Hs
		349800 RASK_HUMAN (1-189): 8.4e-77: 229: 100.00		INSR_HUMAN (467-747): 2.53e-53: 204: 39.15
+	Hs
		349905 RASK_HUMAN (1-189): 8.4e-77: 229: 100.00		EPHB2_HUMAN (466-746): 4.25e-53: 203: 40.70
+	Hs
		665570 RAB2A_HUMAN (4-183): 1.46e-75: 227: 32.97		EPHB2_HUMAN (466-746): 4.25e-53: 203: 40.70
+	Hs
		349808 RASK_HUMAN (1-189): 8.4e-77: 229: 100.00		IGF1R_HUMAN (467-747): 1.28e-51: 199: 37.68