HitPredict

Interactor 1: DLGP3 (O95886)
Disks large-associated protein 3 (DAP-3) (PSD-95/SAP90-binding protein 3) (SAP90/PSD-95-associated protein 3) (SAPAP3)
Gene: DLGAP3

Interactor 2: DLG2 (Q15700)
Disks large homolog 2 (Channel-associated protein of synapse-110) (Chapsyn-110) (Postsynaptic density protein PSD-93)
Gene: DLG2

Species: Homo sapiens

Source: intact

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.61	0.60	0.606

Property	Details
Experiments	32296183, unassigned1304
Identification Methods	two hybrid, two hybrid prey pooling approach, two hybrid array, validated two hybrid
Interaction Type	direct interaction, physical association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0005886 - plasma membrane GO:0014069 - postsynaptic density GO:0031594 - neuromuscular junction
Homologous interactions	20

Homologous interactions (Top 20)

Color coding for hit scores

	1 979 Hs			1 870
+	Hs
		1152422 DLGP2_HUMAN (1-979): 0: 1097: 45.66		DLG2_HUMAN (1-870): 0: 732: 100.00
+	Rn
		1021983 DLGP3_RAT (1-979): 0: 1248: 94.18		DLG1_RAT (9-870): 2.17e-166: 508: 51.65
+	Rn
		1021978 DLGP2_RAT (1-979): 0: 1105: 45.64		DLG1_RAT (9-870): 2.17e-166: 508: 51.65
+	Hs
		1091587 DLGP2_HUMAN (1-979): 0: 1097: 45.66		DLG1_HUMAN (7-870): 8.32e-166: 507: 52.11
+	Hs
		4753 A0A1B0GTN4_HUMAN (1-979): 0: 1097: 45.66		DLG1_HUMAN (7-870): 8.32e-166: 507: 52.11
+	Hs
		350655 DLGP3_HUMAN (1-979): 0: 1309: 100.00		DLG4_HUMAN (13-446): 1.73e-30: 130: 16.52
+	Mm
		1223565 DLGP3_MOUSE (1-979): 0: 1269: 94.49		DLG4_MOUSE (13-446): 2.95e-30: 129: 16.52
+	Rn
		723873 DLGP3_RAT (1-979): 0: 1248: 94.18		DLG4_RAT (13-446): 5.09e-30: 129: 16.52
+	Rn
		1021984 DLGP3_RAT (1-979): 0: 1248: 94.18		DLG3_RAT (270-492): 1.6e-12: 73.7: 16.59
+	Rn
		723872 DLGP2_RAT (1-979): 0: 1105: 45.64		DLG4_RAT (13-446): 5.09e-30: 129: 16.52
+	Mm
		1223616 DLGP2_MOUSE (1-979): 0: 1101: 45.35		DLG4_MOUSE (13-446): 2.95e-30: 129: 16.52
+	Hs
		1006115 DLGP2_HUMAN (1-979): 0: 1097: 45.66		DLG4_HUMAN (13-446): 1.73e-30: 130: 16.52
+	Hs
		1368727 DLGP2_HUMAN (1-979): 0: 1097: 45.66		DLG3_HUMAN (11-444): 5.43e-30: 129: 15.08
+	Hs
		4755 A0A1B0GTN4_HUMAN (1-979): 0: 1097: 45.66		DLG3_HUMAN (11-444): 5.43e-30: 129: 15.08
+	Hs
		154393 DLGP1_HUMAN (1-979): 0: 1091: 38.63		DLG4_HUMAN (13-446): 1.73e-30: 130: 16.52
+	Hs
		1212217 DLGP2_HUMAN (1-979): 0: 1097: 45.66		MPP7_HUMAN (14-410): 2.28e-26: 116: 10.58
+	Hs
		4754 A0A1B0GTN4_HUMAN (1-979): 0: 1097: 45.66		MPP7_HUMAN (14-410): 2.28e-26: 116: 10.58
+	Hs
		168762 DLGP2_HUMAN (1-979): 0: 1097: 45.66		CSKP_HUMAN (6-307): 2.26e-24: 111: 10.54
+	Hs
		4749 A0A1B0GTN4_HUMAN (1-979): 0: 1097: 45.66		CSKP_HUMAN (6-307): 2.26e-24: 111: 10.54
+	Rn
		1021979 DLGP2_RAT (1-979): 0: 1105: 45.64		DLG3_RAT (270-492): 1.6e-12: 73.7: 16.59