Interactor 1: FBLN4 (O95967)
EGF-containing fibulin-like extracellular matrix protein 2 (Fibulin-4) (FIBL-4) (Protein UPH1)
Gene: EFEMP2
Interactor 2: FBN1 (P35555)
Fibrillin-1 [Cleaved into: Asprosin]
Gene: FBN1
Species: Homo sapiens
Source: intact
Category: Small-scale
Confidence: High
| Method score | Annotation score | Interaction score |
|---|---|---|
| 0.52 | 1.00 | 0.724 |
The method score is based on:
| Property | Details |
|---|---|
| Experiments | 19570982 |
| Identification Methods | surface plasmon resonance, enzyme linked immunosorbent assay |
| Interaction Type | direct interaction, physical association |
The annotation score is based on:
| Property | Details |
|---|---|
| Interacting Pfam domains | EGF_3~EGF_CA, EGF_CA~EGF_CA, EGF_CA~FXa_inhibition, EGF_CA~hEGF, EGF_CA~TB |
| Common GO terms | GO:0001527 - microfibril GO:0005201 - extracellular matrix structural constituent GO:0005509 - calcium ion binding GO:0005576 - extracellular region GO:0005604 - basement membrane and 2 others more... |
| Homologous interactions | 17 |
Homologous interactions
Color coding for hit scores 
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Service provided by Combinatics, Japan
Last updated: 11Aug2025
