HitPredict

Interactor 1: O96692 (O96692)
small monomeric GTPase (EC 3.6.5.2)
Gene: Rap2l

Interactor 2: Q9VFD3 (Q9VFD3)
Uncharacterized protein, isoform B
Gene: DmelCG42788

Species: Drosophila melanogaster

Source: biogrid

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.38	0.80	0.555

Property	Details
Experiments	15710747
Identification Methods	two hybrid
Interaction Type	direct interaction

Property	Details
Interacting Pfam domains	FERM_M~Ras, PDZ~Ras, RA_2~Ras
Common GO terms	-
Homologous interactions	20

Homologous interactions (Top 20)

Color coding for hit scores

	1 182 Dm			1 1560
+	Dm
		473572 RAP1_DROME (1-165): 9.71e-66: 201: 58.18		Q9VFD3_DROME (1-1560): 0: 1671: 100.00
+	Hs
		956501 RAB2A_HUMAN (4-170): 1.12e-75: 227: 33.93		E41L5_HUMAN (354-1041): 5.51e-107: 360: 15.05
+	Hs
		976578 RB11A_HUMAN (4-176): 1.49e-74: 224: 32.76		E41L5_HUMAN (354-1041): 5.51e-107: 360: 15.05
+	Dm
		119956 O96692_DROME (16-182): 5.2e-86: 252: 100.00		M9PBW9_DROME (371-883): 6.72e-71: 266: 13.95
+	Hs
		217415 RAB2A_HUMAN (4-170): 1.12e-75: 227: 33.93		E41L2_HUMAN (236-942): 6.64e-79: 285: 12.20
+	Hs
		374210 RASN_HUMAN (1-174): 8.4e-45: 148: 47.13		E41L5_HUMAN (354-1041): 5.51e-107: 360: 15.05
+	Hs
		956491 RAB2A_HUMAN (4-170): 1.12e-75: 227: 33.93		E41L1_HUMAN (331-1022): 4.37e-78: 280: 12.27
+	Hs
		976560 RB11A_HUMAN (4-176): 1.49e-74: 224: 32.76		E41L1_HUMAN (331-1022): 4.37e-78: 280: 12.27
+	Hs
		767291 RIT1_HUMAN (2-164): 2.59e-53: 170: 48.47		MERL_HUMAN (372-922): 7.25e-87: 298: 12.37
+	Dm
		356008 O96692_DROME (16-182): 5.2e-86: 252: 100.00		Q9W2L2_DROME (18-248): 1.09e-53: 208: 22.89
+	Hs
		373782 RASN_HUMAN (1-174): 8.4e-45: 148: 47.13		MOES_HUMAN (391-991): 2.32e-91: 310: 13.06
+	Hs
		373801 RASN_HUMAN (1-174): 8.4e-45: 148: 47.13		MERL_HUMAN (372-922): 7.25e-87: 298: 12.37
+	Hs
		217359 RASN_HUMAN (1-174): 8.4e-45: 148: 47.13		E41L2_HUMAN (236-942): 6.64e-79: 285: 12.20
+	Hs
		374195 RASN_HUMAN (1-174): 8.4e-45: 148: 47.13		E41L1_HUMAN (331-1022): 4.37e-78: 280: 12.27
+	Hs
		902229 RAB13_HUMAN (4-176): 5.73e-76: 227: 30.46		WWOX_HUMAN (173-338): 5.86e-45: 170: 23.46
+	Dm
		874122 RALA_DROME (5-182): 1.05e-46: 153: 42.33		Q9W2L2_DROME (18-248): 1.09e-53: 208: 22.89
+	Mm
		861888 RAP2A_MOUSE (1-178): 3.56e-76: 227: 69.66		NEDD4_MOUSE (110-265): 9.84e-21: 101: 23.43
+	Hs
		518585 RAP2A_HUMAN (1-178): 2.2e-71: 215: 69.66		NEDD4_HUMAN (157-265): 9.36e-20: 98.7: 23.58
+	Hs
		373827 RASN_HUMAN (1-174): 8.4e-45: 148: 47.13		NEDD4_HUMAN (157-265): 9.36e-20: 98.7: 23.58
+	Hs
		374137 RASN_HUMAN (1-174): 8.4e-45: 148: 47.13		ITCH_HUMAN (5-217): 3.29e-10: 67.2: 13.44