HitPredict

Interactor 1: H4 (P02309)
Histone H4
Gene: HHF1

Interactor 2: HDA1 (P53973)
Histone deacetylase HDA1 (EC 3.5.1.98)
Gene: HDA1

Species: Saccharomyces cerevisiae S288C

Source: intact

Category: Small-scale

Confidence: High

Method score	Annotation score	Interaction score
0.56	0.50	0.534

Property	Details
Experiments	27665728, 21179020
Identification Methods	pull down, tandem affinity purification
Interaction Type	direct interaction, association

Property	Details
Interacting Pfam domains	-
Common GO terms	-
Homologous interactions	12

Homologous interactions

Color coding for hit scores

	1 103 Sc			1 706
+	Hs
		880666 H4_HUMAN (18-103): 1.92e-41: 133: 90.70		HDAC4_HUMAN (29-460): 2.55e-161: 495: 34.93
+	Hs
		918151 H4_HUMAN (18-103): 1.92e-41: 133: 90.70		HDAC5_HUMAN (19-444): 1.54e-146: 457: 33.33
+	Hs
		918121 H4_HUMAN (18-103): 1.92e-41: 133: 90.70		HDAC9_HUMAN (27-425): 1.48e-144: 449: 34.27
+	Mm
		140249 H4_MOUSE (18-103): 1.92e-41: 133: 90.70		HDAC1_MOUSE (64-450): 2.3e-147: 439: 23.70
+	Hs
		917226 H4_HUMAN (18-103): 1.92e-41: 133: 90.70		HDAC1_HUMAN (64-450): 2.35e-147: 439: 23.70
+	Sc
		356336 H4_YEAST (1-103): 5.28e-47: 147: 100.00		RPD3_YEAST (46-401): 1.41e-139: 417: 24.44
+	Dm
		950398 H4_DROME (18-103): 2.42e-41: 133: 90.70		HDAC1_DROME (65-453): 1.71e-142: 428: 23.10
+	Hs
		917682 H4_HUMAN (18-103): 1.92e-41: 133: 90.70		HDAC2_HUMAN (65-456): 1.84e-134: 406: 23.17
+	Mm
		918237 H4_MOUSE (18-103): 1.92e-41: 133: 90.70		HDAC2_MOUSE (65-456): 9.36e-134: 405: 23.17
+	Hs
		918077 H4_HUMAN (18-103): 1.92e-41: 133: 90.70		HDAC6_HUMAN (58-438): 1.5e-119: 388: 34.12
+	Sp
		140573 H4_SCHPO (18-103): 2.79e-41: 133: 90.70		PHD1_SCHPO (65-403): 4.26e-36: 143: 28.20
+	Sc
		356604 H4_YEAST (1-103): 5.28e-47: 147: 100.00		HOS2_YEAST (62-385): 1.06e-30: 127: 27.27