HitPredict

Interactor 1: HSP82 (P02829)
ATP-dependent molecular chaperone HSP82 (82 kDa heat shock protein) (Heat shock protein Hsp90 heat-inducible isoform)
Gene: HSP82

Interactor 2: NNK1 (P36003)
Nitrogen network kinase 1 (EC 2.7.11.1)
Gene: NNK1

Species: Saccharomyces cerevisiae S288C

Source: biogrid

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.41	1.00	0.647

Property	Details
Experiments	16319894
Identification Methods	enzymatic study
Interaction Type	direct interaction

Property	Details
Interacting Pfam domains	HSP90~Pkinase
Common GO terms	GO:0005524 - ATP binding GO:0005634 - nucleus GO:0005737 - cytoplasm
Homologous interactions	20

Homologous interactions (Top 20)

Color coding for hit scores

	1 709 Sc			1 928
+	Hs
		438350 HS90B_HUMAN (5-709): 0: 1026: 62.13		DCLK2_HUMAN (85-797): 1.08e-145: 452: 14.40
+	Hs
		432057 HS90A_HUMAN (4-709): 0: 1015: 60.83		DCLK2_HUMAN (85-797): 1.08e-145: 452: 14.40
+	Hs
		438643 HS90B_HUMAN (5-709): 0: 1026: 62.13		M3K2_HUMAN (162-713): 6.18e-108: 348: 17.30
+	Hs
		432386 HS90A_HUMAN (4-709): 0: 1015: 60.83		M3K2_HUMAN (162-713): 6.18e-108: 348: 17.30
+	Hs
		438147 HS90B_HUMAN (5-709): 0: 1026: 62.13		KCC2G_HUMAN (447-814): 5.11e-103: 333: 19.75
+	Hs
		431826 HS90A_HUMAN (4-709): 0: 1015: 60.83		KCC2G_HUMAN (447-814): 5.11e-103: 333: 19.75
+	Hs
		438541 HS90B_HUMAN (5-709): 0: 1026: 62.13		SGK2_HUMAN (411-746): 2.21e-90: 293: 19.84
+	Hs
		438146 HS90B_HUMAN (5-709): 0: 1026: 62.13		KCC2B_HUMAN (447-814): 3.7e-86: 291: 18.52
+	Hs
		116958 HS90B_HUMAN (5-709): 0: 1026: 62.13		SGK1_HUMAN (396-744): 1.76e-86: 285: 19.53
+	Hs
		432275 HS90A_HUMAN (4-709): 0: 1015: 60.83		SGK2_HUMAN (411-746): 2.21e-90: 293: 19.84
+	Hs
		431825 HS90A_HUMAN (4-709): 0: 1015: 60.83		KCC2B_HUMAN (447-814): 3.7e-86: 291: 18.52
+	Hs
		116956 HS90A_HUMAN (4-709): 0: 1015: 60.83		SGK1_HUMAN (396-744): 1.76e-86: 285: 19.53
+	Hs
		438026 HS90B_HUMAN (5-709): 0: 1026: 62.13		AAPK2_HUMAN (441-627): 4.6e-54: 199: 21.69
+	Hs
		438123 HS90B_HUMAN (5-709): 0: 1026: 62.13		AAPK1_HUMAN (441-627): 5.73e-54: 199: 21.16
+	Hs
		438443 HS90B_HUMAN (5-709): 0: 1026: 62.13		TSSK3_HUMAN (448-627): 1.32e-54: 192: 23.91
+	Hs
		431689 HS90A_HUMAN (4-709): 0: 1015: 60.83		AAPK2_HUMAN (441-627): 4.6e-54: 199: 21.69
+	Hs
		431800 HS90A_HUMAN (4-709): 0: 1015: 60.83		AAPK1_HUMAN (441-627): 5.73e-54: 199: 21.16
+	Hs
		432170 HS90A_HUMAN (4-709): 0: 1015: 60.83		TSSK3_HUMAN (448-627): 1.32e-54: 192: 23.91
+	Sc
		365813 HSP82_YEAST (1-709): 0: 984: 100.00		KCC2_YEAST (412-645): 1.53e-61: 217: 22.63
+	Sc
		365561 HSP82_YEAST (1-709): 0: 984: 100.00		SNF1_YEAST (443-627): 3.62e-56: 207: 23.00