Protein: ATX2L
Ataxin-2-like protein (Ataxin-2 domain protein) (Ataxin-2-related protein)

Gene: ATX2L, ATXN2L
Organism: Homo sapiens
Interactions: 230
UniProt ID: Q8WWM7

Gene Ontology (top 5):
GO:0003723 - RNA binding
GO:0003729 - mRNA binding
GO:0005829 - cytosol
GO:0010494 - cytoplasmic stress granule
GO:0016020 - membrane

Download interactions: TXT   MITAB-2.5

Interaction Interactor Experiments Homologs Category Interaction
Score
Confidence

516606

PABP1
Polyadenylate-binding protein 1

2

13

Small-scale

0.776

High

640560

DDX6
Probable ATP-dependent RNA helicase DDX6

7

8

Small-scale

0.741

High

1262706

ATX2
Ataxin-2

2

9

Small-scale

0.737

High

1262738

G3BP2
Ras GTPase-activating protein-binding protein 2

6

7

High-throughput

0.735

High

1189880

NUFP2
FMR1-interacting protein NUFIP2

5

1

High-throughput

0.718

High

1030384

G3BP1
Ras GTPase-activating protein-binding protein 1

5

7

Small-scale

0.714

High

1109609

LSM12
Protein LSM12

4

4

High-throughput

0.694

High

1031402

PABP4
Polyadenylate-binding protein 4

1

13

High-throughput

0.691

High

989032

FMR1
Fragile X messenger ribonucleoprotein 1

3

12

High-throughput

0.650

High

304265

UBR5
E3 ubiquitin-protein ligase UBR5

1

6

Small-scale

0.618

High

398048

ISG15
Ubiquitin-like protein ISG15

2

6

High-throughput

0.601

High

529484

CFTR
Cystic fibrosis transmembrane conductance regulator

2

3

High-throughput

0.601

High

1241235

FA98A
Protein FAM98A

2

1

Small-scale

0.601

High

228191

PRKN
E3 ubiquitin-protein ligase parkin

2

9

High-throughput

0.584

High

1262734

ZRAN1
Ubiquitin thioesterase ZRANB1

2

6

High-throughput

0.584

High

888666

KR124
Keratin-associated protein 12-4

2

0

High-throughput

0.580

High

718048

BMI1
Polycomb complex protein BMI-1

2

5

High-throughput

0.571

High

726955

FUS
RNA-binding protein FUS

2

17

High-throughput

0.571

High

647144

1433T
14-3-3 protein theta

1

19

High-throughput

0.554

High

683578

1433B
14-3-3 protein beta/alpha

1

19

High-throughput

0.554

High

904919

1433G
14-3-3 protein gamma

1

19

High-throughput

0.554

High

909862

1433E
14-3-3 protein epsilon

1

2

High-throughput

0.554

High

982330

1433F
14-3-3 protein eta

1

19

High-throughput

0.554

High

1238766

BOLL
Protein boule-like

2

14

High-throughput

0.553

High

931300

YBOX1
Y-box-binding protein 1

2

2

Small-scale

0.552

High

87479

MCRI1
Mapk-regulated corepressor-interacting protein 1

1

2

High-throughput

0.536

High

155057

NDC80
Kinetochore protein NDC80 homolog

1

3

High-throughput

0.536

High

236809

CCNT1
Cyclin-T1

1

2

High-throughput

0.536

High

781785

MNDA
Myeloid cell nuclear differentiation antigen

1

4

High-throughput

0.536

High

791808

HD
Huntingtin

1

2

High-throughput

0.536

High

813636

CAPZB
F-actin-capping protein subunit beta

1

3

High-throughput

0.536

High

958738

2ABB
Serine/threonine-protein phosphatase 2A 55 kDa regulatory subunit B beta isoform

1

2

High-throughput

0.536

High

1042150

CUL3
Cullin-3

1

4

High-throughput

0.536

High

1146363

2ABD
Serine/threonine-protein phosphatase 2A 55 kDa regulatory subunit B delta isoform

1

2

High-throughput

0.536

High

1262710

MCRI2
MAPK regulated corepressor interacting protein 2

1

2

High-throughput

0.536

High

581805

VCAM1
Vascular cell adhesion protein 1

2

2

High-throughput

0.521

High

581170

EPOR
Erythropoietin receptor

1

1

Small-scale

0.515

High

950229

SMAD3
Mothers against decapentaplegic homolog 3

1

1

Small-scale

0.515

High

868647

ATX1
Ataxin-1

1

2

High-throughput

0.508

High

771156

TPOR
Thrombopoietin receptor

1

1

Small-scale

0.504

High

175071

OGT1
UDP-N-acetylglucosamine--peptide N-acetylglucosaminyltransferase 110 kDa subunit

1

8

High-throughput

0.501

High

829954

HXA1
Homeobox protein Hox-A1

1

3

High-throughput

0.494

High

295817

ST17B
Serine/threonine-protein kinase 17B

1

2

High-throughput

0.489

High

307267

RCBT2
RCC1 and BTB domain-containing protein 2

1

2

High-throughput

0.489

High

617343

SP100
Nuclear autoantigen Sp-100

1

14

High-throughput

0.489

High

1050727

FHL2
Four and a half LIM domains protein 2

1

8

High-throughput

0.489

High

1061861

SLMAP
Sarcolemmal membrane-associated protein

1

1

High-throughput

0.489

High

1262717

KTBL1
KATNB1-like protein 1

1

1

High-throughput

0.489

High

1262733

FBLN5
Fibulin-5

1

3

High-throughput

0.489

High

123295

CBX4
E3 SUMO-protein ligase CBX4

1

5

High-throughput

0.479

High

125600

WWP2
NEDD4-like E3 ubiquitin-protein ligase WWP2

1

4

High-throughput

0.479

High

149108

CTRO
Citron Rho-interacting kinase

1

6

High-throughput

0.479

High

199793

SNUT1
U4/U6.U5 tri-snRNP-associated protein 1

1

2

High-throughput

0.479

High

204712

E41L2
Band 4.1-like protein 2

1

6

High-throughput

0.479

High

210162

PRC1
Protein regulator of cytokinesis 1

1

3

High-throughput

0.479

High

214331

SPOP
Speckle-type POZ protein

1

4

High-throughput

0.479

High

215000

CPSF5
Cleavage and polyadenylation specificity factor subunit 5

1

1

High-throughput

0.479

High

232950

PHLP1
PH domain leucine-rich repeat-containing protein phosphatase 1

1

7

High-throughput

0.479

High

237409

CCNT2
Cyclin-T2

1

2

High-throughput

0.479

High

263756

PR40A
Pre-mRNA-processing factor 40 homolog A

1

8

High-throughput

0.479

High

295060

RECQ4
ATP-dependent DNA helicase Q4

1

7

High-throughput

0.479

High

322926

STAU1
Double-stranded RNA-binding protein Staufen homolog 1

1

9

High-throughput

0.479

High

370092

ESR1
Estrogen receptor

1

20

High-throughput

0.479

High

374605

RAF1
RAF proto-oncogene serine/threonine-protein kinase

1

9

High-throughput

0.479

High

402283

JUN
Transcription factor Jun

1

9

High-throughput

0.479

High

456616

UCHL1
Ubiquitin carboxyl-terminal hydrolase isozyme L1

1

2

Small-scale

0.479

High

504475

HSP7C
Heat shock cognate 71 kDa protein

1

3

High-throughput

0.479

High

522098

CADH1
Cadherin-1

1

2

High-throughput

0.479

High

530706

ITA4
Integrin alpha-4

1

2

High-throughput

0.479

High

591032

BTF3
Transcription factor BTF3

1

1

High-throughput

0.479

High

615800

GCSP
Glycine dehydrogenase

1

1

High-throughput

0.479

High

632830

TYY1
Transcriptional repressor protein YY1

1

3

High-throughput

0.479

High

668397

RBMS1
RNA-binding motif, single-stranded-interacting protein 1

1

16

High-throughput

0.479

High

684237

1433S
14-3-3 protein sigma

1

19

High-throughput

0.479

High

717238

CTNB1
Catenin beta-1

1

4

High-throughput

0.479

High

719018

PHB1
Prohibitin 1

1

3

High-throughput

0.479

High

749713

BRCA1
Breast cancer type 1 susceptibility protein

1

5

High-throughput

0.479

High

759753

RS19
Small ribosomal subunit protein eS19

1

2

High-throughput

0.479

High

779812

CCNF
Cyclin-F

1

3

High-throughput

0.479

High

808798

YAP1
Transcriptional coactivator YAP1

1

11

High-throughput

0.479

High

818301

SOX2
Transcription factor SOX-2

1

20

High-throughput

0.479

High

833489

RBM25
RNA-binding protein 25

1

11

High-throughput

0.479

High

841823

CDK9
Cyclin-dependent kinase 9

1

2

High-throughput

0.479

High

843814

FXR1
RNA-binding protein FXR1

1

12

High-throughput

0.479

High

868273

ATX3
Ataxin-3

1

1

High-throughput

0.479

High

875694

MFAP1
Microfibrillar-associated protein 1

1

1

High-throughput

0.479

High

893098

RS20
Small ribosomal subunit protein uS10

1

2

High-throughput

0.479

High

897789

ABCE1
ATP-binding cassette sub-family E member 1

1

1

High-throughput

0.479

High

908884

UBE2H
Ubiquitin-conjugating enzyme E2 H

1

2

High-throughput

0.479

High

916286

RL23A
Large ribosomal subunit protein uL23

1

1

High-throughput

0.479

High

923445

RL8
Large ribosomal subunit protein uL2

1

1

High-throughput

0.479

High

927346

1433Z
14-3-3 protein zeta/delta

1

19

High-throughput

0.479

High

957742

XIAP
E3 ubiquitin-protein ligase XIAP

1

2

Small-scale

0.479

High

961211

HSF1
Heat shock factor protein 1

1

1

High-throughput

0.479

High

969885

KIF23
Kinesin-like protein KIF23

1

6

High-throughput

0.479

High

1024384

UBP4
Ubiquitin carboxyl-terminal hydrolase 4

1

3

High-throughput

0.479

High

1025870

TADBP
TAR DNA-binding protein 43

1

12

High-throughput

0.479

High

1037854

PRP4K
Serine/threonine-protein kinase PRP4 homolog

1

7

High-throughput

0.479

High

1049850

UBP2L
Ubiquitin-associated protein 2-like

1

12

High-throughput

0.479

High

1052269

SRC8
Src substrate cortactin

1

17

High-throughput

0.479

High

1054463

RBM39
RNA-binding protein 39

1

14

High-throughput

0.479

High

1056706

PUM1
Pumilio homolog 1

1

3

High-throughput

0.479

High

1063988

TNIP1
TNFAIP3-interacting protein 1

1

7

High-throughput

0.479

High

1066456

KIF14
Kinesin-like protein KIF14

1

3

High-throughput

0.479

High

1069753

NONO
Non-POU domain-containing octamer-binding protein

1

16

High-throughput

0.479

High

1071944

PCBP1
Poly(rC)-binding protein 1

1

6

High-throughput

0.479

High

1084545

CPSF6
Cleavage and polyadenylation specificity factor subunit 6

1

17

High-throughput

0.479

High

1116412

LARP7
La-related protein 7

1

18

High-throughput

0.479

High

1126287

FA76B
Protein FAM76B

1

1

High-throughput

0.479

High

1136195

RC3H1
Roquin-1

1

3

High-throughput

0.479

High

1137386

MEX3C
RNA-binding E3 ubiquitin-protein ligase MEX3C

1

4

Small-scale

0.479

High

1164851

FIP1
Pre-mRNA 3'-end-processing factor FIP1

1

1

High-throughput

0.479

High

1168800

MEX3B
RNA-binding protein MEX3B

1

3

High-throughput

0.479

High

1198456

PEG10
Retrotransposon-derived protein PEG10

1

1

Small-scale

0.479

High

1200525

NAA40
N-alpha-acetyltransferase 40

1

1

High-throughput

0.479

High

1204679

DDX42
ATP-dependent RNA helicase DDX42

1

3

High-throughput

0.479

High

1219202

Z3H7A
Zinc finger CCCH domain-containing protein 7A

1

7

High-throughput

0.479

High

1221597

SMC5
Structural maintenance of chromosomes protein 5

1

5

High-throughput

0.479

High

1224174

DCP1B
mRNA-decapping enzyme 1B

1

10

High-throughput

0.479

High

1235753

CPSF7
Cleavage and polyadenylation specificity factor subunit 7

1

11

High-throughput

0.479

High

1240889

SERB1
SERPINE1 mRNA-binding protein 1

1

2

High-throughput

0.479

High

1250961

SNIP1
Smad nuclear-interacting protein 1

1

2

High-throughput

0.479

High

1251809

FA76A
Protein FAM76A

1

1

High-throughput

0.479

High

1255629

RBCC1
RB1-inducible coiled-coil protein 1

1

9

High-throughput

0.479

High

1259851

PPIL4
Peptidyl-prolyl cis-trans isomerase-like 4

1

3

High-throughput

0.479

High

1262685

PSPC1
Paraspeckle component 1

1

16

High-throughput

0.479

High

1262686

BAP1
Ubiquitin carboxyl-terminal hydrolase BAP1

1

2

High-throughput

0.479

High

1262689

REQU
Zinc finger protein ubi-d4

1

6

High-throughput

0.479

High

1262690

DAZL
Deleted in azoospermia-like

1

17

High-throughput

0.479

High

1262691

FUBP1
Far upstream element-binding protein 1

1

7

High-throughput

0.479

High

1262693

AP2M1
AP-2 complex subunit mu

1

2

High-throughput

0.479

High

1262695

SPDLY
Protein Spindly

1

1

High-throughput

0.479

High

1262697

RNF31
E3 ubiquitin-protein ligase RNF31

1

6

High-throughput

0.479

High

1262698

EDC3
Enhancer of mRNA-decapping protein 3

1

1

High-throughput

0.479

High

1262702

PP1RA
Serine/threonine-protein phosphatase 1 regulatory subunit 10

1

4

High-throughput

0.479

High

1262705

NECD
Necdin

1

2

High-throughput

0.479

High

1262707

MYD88
Myeloid differentiation primary response protein MyD88

1

2

Small-scale

0.479

High

1262708

ANM1
Protein arginine N-methyltransferase 1

1

4

High-throughput

0.479

High

1262711

PINK1
Serine/threonine-protein kinase PINK1, mitochondrial

1

2

High-throughput

0.479

High

1262712

ACE2
Angiotensin-converting enzyme 2

1

1

High-throughput

0.479

High

1262713

KPCD2
Serine/threonine-protein kinase D2

1

1

High-throughput

0.479

High

1262714

UNK
RING finger protein unkempt homolog

1

5

High-throughput

0.479

High

1262716

WWTR1
WW domain-containing transcription regulator protein 1

1

11

High-throughput

0.479

High

1262718

NSRP1
Nuclear speckle splicing regulatory protein 1

1

1

High-throughput

0.479

High

1262722

ECT2
Protein ECT2

1

5

High-throughput

0.479

High

1262724

RC3H2
Roquin-2

1

12

High-throughput

0.479

High

1262725

DCP1A
mRNA-decapping enzyme 1A

1

6

High-throughput

0.479

High

1262726

ANLN
Anillin

1

2

High-throughput

0.479

High

1262727

SIR7
NAD-dependent protein deacetylase sirtuin-7

1

5

High-throughput

0.479

High

1262729

DCA13
DDB1- and CUL4-associated factor 13

1

5

High-throughput

0.479

High

1262731

DDX56
Probable ATP-dependent RNA helicase DDX56

1

6

High-throughput

0.479

High

1262735

MKRN1
E3 ubiquitin-protein ligase makorin-1

1

5

Small-scale

0.479

High

1262736

HECD1
E3 ubiquitin-protein ligase HECTD1

1

8

High-throughput

0.479

High

1262737

FZR1
Fizzy-related protein homolog

1

10

High-throughput

0.479

High

1262740

FBW1A
F-box/WD repeat-containing protein 1A

1

5

High-throughput

0.479

High

1262741

KLH20
Kelch-like protein 20

1

2

High-throughput

0.479

High

1262742

YTHD2
YTH domain-containing family protein 2

1

6

High-throughput

0.479

High

182844

R113A
E3 ubiquitin-protein ligase RNF113A

1

0

High-throughput

0.458

High

508629

TOP1
DNA topoisomerase 1

1

0

High-throughput

0.458

High

786043

LAP2B
Lamina-associated polypeptide 2, isoforms beta/gamma

1

0

High-throughput

0.458

High

822334

KC1D
Casein kinase I isoform delta

1

0

High-throughput

0.458

High

848093

MECP2
Methyl-CpG-binding protein 2

1

0

High-throughput

0.458

High

929338

IF5A1
Eukaryotic translation initiation factor 5A-1

1

0

High-throughput

0.458

High

943797

CCNA1
Cyclin-A1

1

0

High-throughput

0.458

High

1026329

AIMP2
Aminoacyl tRNA synthase complex-interacting multifunctional protein 2

1

0

Small-scale

0.458

High

1184230

MEPCE
7SK snRNA methylphosphate capping enzyme

1

0

High-throughput

0.458

High

1262692

LRC59
Leucine-rich repeat-containing protein 59

1

0

High-throughput

0.458

High

1262703

POP1
Ribonucleases P/MRP protein subunit POP1

1

0

High-throughput

0.458

High

1262709

MMTA2
Multiple myeloma tumor-associated protein 2

1

0

High-throughput

0.458

High

1043992

DYR1A
Dual specificity tyrosine-phosphorylation-regulated kinase 1A

1

5

High-throughput

0.445

High

1124570

ODFP2
Outer dense fiber protein 2

1

1

High-throughput

0.445

High

1130380

LRRK2
Leucine-rich repeat serine/threonine-protein kinase 2

1

4

High-throughput

0.445

High

1145859

CP135
Centrosomal protein of 135 kDa

1

1

High-throughput

0.445

High

1153306

PKHA7
Pleckstrin homology domain-containing family A member 7

1

17

High-throughput

0.445

High

1169418

NBEL2
Neurobeachin-like protein 2

1

9

High-throughput

0.445

High

1244276

ARI1B
AT-rich interactive domain-containing protein 1B

1

12

High-throughput

0.445

High

1262700

CEP63
Centrosomal protein of 63 kDa

1

5

High-throughput

0.445

High

1262704

ZBT18
Zinc finger and BTB domain-containing protein 18

1

1

High-throughput

0.445

High

1262715

ZDHC5
Palmitoyltransferase ZDHHC5

1

2

High-throughput

0.445

High

1262723

LN28A
Protein lin-28 homolog A

1

2

High-throughput

0.445

High

1262739

DICER
Endoribonuclease Dicer

1

6

Small-scale

0.445

High

778228

ECHA
Trifunctional enzyme subunit alpha, mitochondrial

1

2

High-throughput

0.439

High

1262688

AP2C
Transcription factor AP-2 gamma

1

0

High-throughput

0.438

High

122267

RN103
E3 ubiquitin-protein ligase RNF103

1

2

High-throughput

0.437

High

181116

INSI1
Insulin-induced gene 1 protein

1

1

High-throughput

0.437

High

233559

NUPR1
Nuclear protein 1

1

1

High-throughput

0.437

High

244703

BRD4
Bromodomain-containing protein 4

1

8

High-throughput

0.437

High

297532

TOX4
TOX high mobility group box family member 4

1

13

High-throughput

0.437

High

318685

EYA4
Eyes absent homolog 4

1

12

High-throughput

0.437

High

347441

MYC
Myc proto-oncogene protein

1

9

High-throughput

0.437

High

379658

MYCN
N-myc proto-oncogene protein

1

9

High-throughput

0.437

High

385238

NTRK1
High affinity nerve growth factor receptor

1

4

High-throughput

0.437

High

422428

NFM
Neurofilament medium polypeptide

1

2

High-throughput

0.437

High

553290

RFA2
Replication protein A 32 kDa subunit

1

5

High-throughput

0.437

High

569903

CEBPB
CCAAT/enhancer-binding protein beta

1

9

High-throughput

0.437

High

651795

RFA1
Replication protein A 70 kDa DNA-binding subunit

1

6

High-throughput

0.437

High

721019

RFA3
Replication protein A 14 kDa subunit

1

4

High-throughput

0.437

High

877815

FOXA1
Hepatocyte nuclear factor 3-alpha

1

7

High-throughput

0.437

High

941229

RNF4
E3 ubiquitin-protein ligase RNF4

1

2

High-throughput

0.437

High

1026491

RFA4
Replication protein A 30 kDa subunit

1

5

High-throughput

0.437

High

1053619

GRM2
Metabotropic glutamate receptor 2

1

2

High-throughput

0.437

High

1081341

E2F4
Transcription factor E2F4

1

2

High-throughput

0.437

High

1158789

TAF2
Transcription initiation factor TFIID subunit 2

1

2

High-throughput

0.437

High

1166700

WDR82
WD repeat-containing protein 82

1

9

High-throughput

0.437

High

1170999

TRI67
Tripartite motif-containing protein 67

1

7

High-throughput

0.437

High

1174606

H32
Histone H3.2

1

10

Small-scale

0.437

High

1188624

PARPT
Protein mono-ADP-ribosyltransferase TIPARP

1

7

High-throughput

0.437

High

1231284

RHG24
Rho GTPase-activating protein 24

1

2

High-throughput

0.437

High

1236399

SIR6
NAD-dependent protein deacylase sirtuin-6

1

5

High-throughput

0.437

High

1256301

DOT1L
Histone-lysine N-methyltransferase, H3 lysine-79 specific

1

1

High-throughput

0.437

High

1262687

ESR2
Estrogen receptor beta

1

20

High-throughput

0.437

High

1262694

ZBT10
Zinc finger and BTB domain-containing protein 10

1

4

Small-scale

0.437

High

1262719

PKHA4
Pleckstrin homology domain-containing family A member 4

1

11

High-throughput

0.437

High

1262721

MET17
Ribosome assembly protein METTL17, mitochondrial

1

1

High-throughput

0.437

High

1262728

POTE1
Protection of telomeres protein 1

1

1

High-throughput

0.437

High

1262730

KBTB4
Kelch repeat and BTB domain-containing protein 4

1

4

High-throughput

0.437

High

1262732

B3GN2
N-acetyllactosaminide beta-1,3-N-acetylglucosaminyltransferase 2

1

2

High-throughput

0.437

High

200636

CP110
Centriolar coiled-coil protein of 110 kDa

1

0

High-throughput

0.426

High

998132

NCBP1
Nuclear cap-binding protein subunit 1

1

0

High-throughput

0.426

High

1120409

NCBP3
Nuclear cap-binding protein subunit 3

1

0

High-throughput

0.426

High

879141

SUMO3
Small ubiquitin-related modifier 3

1

3

Small-scale

0.407

High

831520

CEBPA
CCAAT/enhancer-binding protein alpha

1

11

High-throughput

0.373

High

303379

HEXI1
Protein HEXIM1

2

0

High-throughput

0.318

High

1202660

TSYL5
Testis-specific Y-encoded-like protein 5

1

0

High-throughput

0.279

Low

1205437

KMT5C
Histone-lysine N-methyltransferase KMT5C

1

0

High-throughput

0.279

Low

1262696

TCAL4
Transcription elongation factor A protein-like 4

1

0

High-throughput

0.279

Low

1262699

IMP1L
Mitochondrial inner membrane protease subunit 1

1

0

High-throughput

0.279

Low

1062177

HAPR1
HUWE1-associated protein modifying stress responses 1

1

0

High-throughput

0.249

Low

1262720

AAMDC
Mth938 domain-containing protein

1

0

High-throughput

0.249

Low

1262701

PTHD1
Patched domain-containing protein 1

1

0

Small-scale

0.232

Low


Service provided by Combinatics, Japan

Last updated: 15 Jul 2024