HitPredict

Interactor 1: HSP82 (P02829)
ATP-dependent molecular chaperone HSP82 (82 kDa heat shock protein) (Heat shock protein Hsp90 heat-inducible isoform)
Gene: HSP82

Interactor 2: RPN1 (P38764)
26S proteasome regulatory subunit RPN1 (HMG-CoA reductase degradation protein 2) (Proteasome non-ATPase subunit 1)
Gene: RPN1

Species: Saccharomyces cerevisiae S288C

Source: intact

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.66	0.60	0.633

Property	Details
Experiments	15766533, 31399574, 19536198
Identification Methods	affinity chromatography technology, tandem affinity purification
Interaction Type	physical association, association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0005634 - nucleus GO:0005737 - cytoplasm
Homologous interactions	6

Homologous interactions

Color coding for hit scores

	1 709 Sc			1 993
+	Sc
		543686 HSC82_YEAST (1-709): 0: 973: 94.64		RPN1_YEAST (1-993): 0: 1053: 100.00
+	Hs
		438460 HS90B_HUMAN (5-709): 0: 1026: 62.13		PSMD1_HUMAN (52-925): 0: 709: 13.42
+	Hs
		432190 HS90A_HUMAN (4-709): 0: 1015: 60.83		PSMD1_HUMAN (52-925): 0: 709: 13.42
+	Sc
		365995 HSP82_YEAST (1-709): 0: 984: 100.00		RPN2_YEAST (52-815): 2.95e-177: 542: 15.54
+	Sc
		543407 HSC82_YEAST (1-709): 0: 973: 94.64		RPN2_YEAST (52-815): 2.95e-177: 542: 15.54
+	Ca
		804512 HSP90_CANAL (4-709): 0: 959: 81.75		Q5A3L0_CANAL (52-816): 9.06e-174: 533: 16.04