Protein: PROZ
Vitamin K-dependent protein Z

Gene: PROZ
Organism: Homo sapiens
Interactions: 41
UniProt ID: P22891

Gene Ontology (top 5):
GO:0004252 - serine-type endopeptidase activity
GO:0005509 - calcium ion binding
GO:0005615 - extracellular space
GO:0005788 - endoplasmic reticulum lumen
GO:0005796 - Golgi lumen

Download interactions: TXT   MITAB-2.5

Interaction Interactor Experiments Homologs Category Interaction
Score
Confidence

653743

EGFL7
Epidermal growth factor-like protein 7

2

19

High-throughput

0.811

High

653744

ZPI
Protein Z-dependent protease inhibitor

1

20

Small-scale

0.730

High

653739

SELN
Selenoprotein N

3

0

High-throughput

0.634

High

534637

BIP
Endoplasmic reticulum chaperone BiP

2

8

High-throughput

0.628

High

653718

TBA4A
Tubulin alpha-4A chain

2

14

High-throughput

0.628

High

653721

MELK
Maternal embryonic leucine zipper kinase

2

1

High-throughput

0.628

High

653722

TBB8
Tubulin beta-8 chain

2

19

High-throughput

0.628

High

653736

SDF2L
Stromal cell-derived factor 2-like protein 1

2

7

High-throughput

0.628

High

653742

DNJB9
DnaJ homolog subfamily B member 9

2

9

High-throughput

0.628

High

161946

MP2K7
Dual specificity mitogen-activated protein kinase kinase 7

2

4

High-throughput

0.574

High

653714

ETV3
ETS translocation variant 3

2

4

High-throughput

0.574

High

653716

FOXG1
Forkhead box protein G1

2

3

High-throughput

0.574

High

653719

FOXF2
Forkhead box protein F2

2

3

High-throughput

0.574

High

653723

KANK2
KN motif and ankyrin repeat domain-containing protein 2

2

6

High-throughput

0.574

High

653735

SIK2
Serine/threonine-protein kinase SIK2

2

1

High-throughput

0.574

High

653737

GNL3L
Guanine nucleotide-binding protein-like 3-like protein

2

1

High-throughput

0.574

High

653740

SENP1
Sentrin-specific protease 1

2

2

High-throughput

0.574

High

653741

SI1L2
Signal-induced proliferation-associated 1-like protein 2

2

1

High-throughput

0.574

High

653749

ATP23
Mitochondrial inner membrane protease ATP23 homolog

2

1

High-throughput

0.574

High

653725

O52W1
Olfactory receptor 52W1

2

1

High-throughput

0.558

High

653720

TBB3
Tubulin beta-3 chain

1

19

High-throughput

0.536

High

653730

N42L2
NEDD4-binding protein 2-like 2

1

2

High-throughput

0.536

High

653738

BCD1
Box C/D snoRNA protein 1

1

2

High-throughput

0.536

High

125877

ARVC
Splicing regulator ARVCF

1

2

High-throughput

0.489

High

653724

IQEC1
IQ motif and SEC7 domain-containing protein 1

1

1

High-throughput

0.489

High

653747

ACOT9
Acyl-coenzyme A thioesterase 9, mitochondrial

1

4

High-throughput

0.489

High

653713

VKGC
Vitamin K-dependent gamma-carboxylase

1

1

High-throughput

0.445

High

575113

IDE
Insulin-degrading enzyme

1

0

High-throughput

0.426

High

653715

SMTN
Smoothelin

1

2

High-throughput

0.407

High

653728

PP4P1
Type 1 phosphatidylinositol 4,5-bisphosphate 4-phosphatase

1

4

High-throughput

0.407

High

653729

PP4P2
Type 2 phosphatidylinositol 4,5-bisphosphate 4-phosphatase

1

4

High-throughput

0.407

High

653732

SDF2
Stromal cell-derived factor 2

1

7

High-throughput

0.407

High

653748

TCAF1
TRPM8 channel-associated factor 1

1

1

High-throughput

0.407

High

653727

RICTR
Rapamycin-insensitive companion of mTOR

3

0

High-throughput

0.345

High

653745

INT6
Integrator complex subunit 6

3

0

High-throughput

0.345

High

653717

MLF1
Myeloid leukemia factor 1

2

0

High-throughput

0.328

High

653731

IP6K3
Inositol hexakisphosphate kinase 3

2

0

High-throughput

0.328

High

653733

CDC6
Cell division control protein 6 homolog

2

0

High-throughput

0.328

High

653726

TYW3
tRNA wybutosine-synthesizing protein 3 homolog

1

0

High-throughput

0.279

Low

653746

HIG1A
HIG1 domain family member 1A, mitochondrial

1

0

High-throughput

0.279

Low

653734

TKTL2
Transketolase-like protein 2

1

0

High-throughput

0.232

Low


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Last updated: 11Aug2025