HitPredict

Interactor 1: FOS (P01100)
Protein c-Fos (Cellular oncogene fos) (Fos proto-oncogene, AP-1 transcription factor subunit) (G0/G1 switch regulatory protein 7) (Proto-oncogene c-Fos) (Transcription factor AP-1 subunit c-Fos)
Gene: FOS

Interactor 2: MMP1 (P03956)
Interstitial collagenase (EC 3.4.24.7) (Fibroblast collagenase) (Matrix metalloproteinase-1) (MMP-1) [Cleaved into: 22 kDa interstitial collagenase; 27 kDa interstitial collagenase]
Gene: MMP1

Species: Homo sapiens

Source: innatedb

Category: Small-scale

Confidence: High

Method score	Annotation score	Interaction score
0.56	0.50	0.533

Property	Details
Experiments	15489293, 11689447
Identification Methods	anti tag coimmunoprecipitation
Interaction Type	physical association

Property	Details
Interacting Pfam domains	-
Common GO terms	-
Homologous interactions	8

Homologous interactions

Color coding for hit scores

	1 380 Hs			1 469
+	Hs
		370595 FOS_HUMAN (1-380): 1.69e-84: 263: 100.00		MMP13_HUMAN (4-466): 0: 621: 47.65
+	Mm
		370841 FOS_MOUSE (1-380): 1.28e-84: 263: 93.68		MMP13_MOUSE (1-466): 0: 619: 47.89
+	Hs
		399262 FOSL1_HUMAN (59-287): 1.44e-34: 130: 37.61		MMP1_HUMAN (1-469): 0: 658: 100.00
+	Hs
		399266 ATF3_HUMAN (131-215): 4.25e-25: 102: 43.53		MMP1_HUMAN (1-469): 0: 658: 100.00
+	Hs
		429474 JUN_HUMAN (48-215): 1.19e-23: 102: 16.47		MMP13_HUMAN (4-466): 0: 621: 47.65
+	Hs
		370535 FOS_HUMAN (1-380): 1.69e-84: 263: 100.00		MMP9_HUMAN (20-206): 5.22e-71: 240: 48.13
+	Hs
		575773 JUND_HUMAN (112-215): 1.8e-13: 72.8: 20.00		MMP9_HUMAN (20-206): 5.22e-71: 240: 48.13
+	Hs
		399524 JUN_HUMAN (48-215): 1.19e-23: 102: 16.47		VTNC_HUMAN (266-437): 1.74e-31: 128: 21.10