Protein: MMP13
Collagenase 3 (EC 3.4.24.-) (Matrix metalloproteinase-13) (MMP-13)

Gene: MMP13
Organism: Homo sapiens
Interactions: 22
UniProt ID: P45452

Gene Ontology (top 5):
GO:0001958 - endochondral ossification
GO:0003417 - growth plate cartilage development
GO:0004175 - endopeptidase activity
GO:0004222 - metalloendopeptidase activity
GO:0004252 - serine-type endopeptidase activity

Download interactions: TXT   MITAB-2.5

Interaction Interactor Experiments Homologs Category Interaction
Score
Confidence

852316

PGCB
Brevican core protein

1

13

Small-scale

0.647

High

337254

ATS2
A disintegrin and metalloproteinase with thrombospondin motifs 2

1

1

High-throughput

0.536

High

504716

FBSP1
F-box/SPRY domain-containing protein 1

1

7

High-throughput

0.536

High

852311

MAEA
E3 ubiquitin-protein transferase MAEA

1

6

High-throughput

0.536

High

852312

ARMC8
Armadillo repeat-containing protein 8

1

1

High-throughput

0.536

High

216641

HTRA2
Serine protease HTRA2, mitochondrial

1

0

High-throughput

0.513

High

287880

MYCB2
E3 ubiquitin-protein ligase MYCBP2

1

0

High-throughput

0.513

High

279688

CISY
Citrate synthase, mitochondrial

1

1

High-throughput

0.489

High

852310

RBP10
Ran-binding protein 10

1

6

High-throughput

0.489

High

852313

GID4
Glucose-induced degradation protein 4 homolog

1

1

High-throughput

0.489

High

852314

SPRY3
SPRY domain-containing protein 3

1

5

High-throughput

0.489

High

852317

PEAK1
Inactive tyrosine-protein kinase PEAK1

1

2

High-throughput

0.489

High

852318

WDR26
WD repeat-containing protein 26

1

2

High-throughput

0.489

High

852319

MKLN1
Muskelin

1

1

High-throughput

0.489

High

403901

GCR
Glucocorticoid receptor

1

3

Small-scale

0.479

High

852320

FBX7
F-box only protein 7

1

1

High-throughput

0.457

High

518771

IL8
Interleukin-8

1

20

Small-scale

0.445

High

370595

FOS
Protein c-Fos

1

8

Small-scale

0.437

High

429474

JUN
Transcription factor Jun

1

6

Small-scale

0.437

High

606384

CEBPB
CCAAT/enhancer-binding protein beta

1

1

Small-scale

0.437

High

852315

KBP
KIF-binding protein

1

0

High-throughput

0.279

Low

852309

NCOA2
Nuclear receptor coactivator 2

1

0

Small-scale

0.249

Low


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Last updated: 11Aug2025