Protein: MMP1
Interstitial collagenase (EC 3.4.24.7) (Fibroblast collagenase) (Matrix metalloproteinase-1) (MMP-1) [Cleaved into: 22 kDa interstitial collagenase; 27 kDa interstitial collagenase]

Gene: MMP1
Organism: Homo sapiens
Interactions: 25
UniProt ID: P03956

Gene Ontology (top 5):
GO:0004175 - endopeptidase activity
GO:0004222 - metalloendopeptidase activity
GO:0004252 - serine-type endopeptidase activity
GO:0005576 - extracellular region
GO:0006508 - proteolysis

Download interactions: TXT   MITAB-2.5

Interaction Interactor Experiments Homologs Category Interaction
Score
Confidence

369989

TIMP1
Metalloproteinase inhibitor 1

2

20

Small-scale

0.830

High

399263

TIMP2
Metalloproteinase inhibitor 2

2

20

Small-scale

0.768

High

399280

TIMP4
Metalloproteinase inhibitor 4

1

20

Small-scale

0.710

High

399279

PGCB
Brevican core protein

1

13

Small-scale

0.647

High

399264

ITA2
Integrin alpha-2

2

12

Small-scale

0.595

High

399261

IL8
Interleukin-8

2

20

Small-scale

0.552

High

399270

CXCL5
C-X-C motif chemokine 5

2

20

Small-scale

0.552

High

370509

FOS
Protein c-Fos

2

8

Small-scale

0.533

High

399260

CO1A2
Collagen alpha-2(I) chain

1

20

Small-scale

0.501

High

399272

SOX8
Transcription factor SOX-8

1

1

High-throughput

0.494

High

399271

NEK4
Serine/threonine-protein kinase Nek4

1

1

High-throughput

0.489

High

399259

GCR
Glucocorticoid receptor

1

3

Small-scale

0.479

High

390313

CXCL7
Platelet basic protein

1

20

Small-scale

0.445

High

399268

CXCL2
C-X-C motif chemokine 2

1

20

Small-scale

0.445

High

399275

CXCL6
C-X-C motif chemokine 6

1

20

Small-scale

0.445

High

399262

FOSL1
Fos-related antigen 1

1

6

Small-scale

0.437

High

399265

CEBPB
CCAAT/enhancer-binding protein beta

1

1

Small-scale

0.437

High

399266

ATF3
Cyclic AMP-dependent transcription factor ATF-3

1

11

Small-scale

0.437

High

399267

CSK22
Casein kinase II subunit alpha'

1

2

High-throughput

0.437

High

399269

BASI
Basigin

1

1

Small-scale

0.437

High

399274

CSK21
Casein kinase II subunit alpha

1

2

High-throughput

0.437

High

399278

CSK23
Casein kinase II subunit alpha 3

1

2

High-throughput

0.437

High

399273

GNAI1
Guanine nucleotide-binding protein G(i) subunit alpha-1

1

0

Small-scale

0.249

Low

399276

TRIP6
Thyroid receptor-interacting protein 6

1

0

Small-scale

0.249

Low

399277

CGAS
Cyclic GMP-AMP synthase

1

0

High-throughput

0.249

Low


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Last updated: 11Aug2025