HitPredict

Interactor 1: CFAD (P03953)
Complement factor D (EC 3.4.21.46) (28 kDa adipocyte protein) (Adipsin) (C3 convertase activator) (Properdin factor D)
Gene: Cfd

Interactor 2: SNED1 (Q70E20)
Sushi, nidogen and EGF-like domain-containing protein 1 (Secreted protein SST-3) (Stromal nidogen extracellular matrix protein)
Gene: SNED1

Species: Mus musculus

Source: biogrid

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.38	1.00	0.618

Property	Details
Experiments	30550785
Identification Methods	affinity chromatography technology
Interaction Type	physical association

Property	Details
Interacting Pfam domains	EGF~Trypsin
Common GO terms	GO:0007219 - Notch signaling pathway
Homologous interactions	17

Homologous interactions

Color coding for hit scores

	1 259 Mm			1 1403
+	Mm
		372030 CFAD_MOUSE (1-259): 1.11e-108: 315: 100.00		Q7TQG5_MOUSE (903-1327): 1.36e-45: 182: 16.52
+	Mm
		192824 CFAD_MOUSE (1-259): 1.11e-108: 315: 100.00		NOTC2_MOUSE (128-706): 1.46e-40: 166: 22.71
+	Mm
		94698 CFAD_MOUSE (1-259): 1.11e-108: 315: 100.00		F2Z4A3_MOUSE (423-588): 7.03e-34: 145: 28.49
+	Hs
		1055016 TMPS4_HUMAN (9-252): 1.75e-97: 293: 35.06		FAT1_HUMAN (424-588): 1.16e-33: 144: 29.24
+	Hs
		980428 TM11B_HUMAN (13-253): 7.08e-99: 296: 31.73		NOTC2_HUMAN (537-1049): 7.21e-33: 141: 22.41
+	Hs
		1055020 KLK11_HUMAN (23-256): 1.47e-96: 285: 32.37		FAT1_HUMAN (424-588): 1.16e-33: 144: 29.24
+	Hs
		489982 TM11B_HUMAN (13-253): 7.08e-99: 296: 31.73		PTPRF_HUMAN (1017-1403): 3.82e-20: 99.8: 7.51
+	Hs
		486154 GRAB_HUMAN (24-250): 8.92e-44: 150: 34.48		NOTC1_HUMAN (358-1063): 1.46e-59: 228: 29.00
+	Hs
		1198224 TM11B_HUMAN (13-253): 7.08e-99: 296: 31.73		JAG2_HUMAN (680-1031): 1.7e-13: 77.8: 16.34
+	Hs
		371464 KLKB1_HUMAN (3-256): 5.99e-100: 306: 30.30		FBN2_HUMAN (698-955): 1.19e-09: 65.3: 18.75
+	Hs
		1345092 TMPS4_HUMAN (9-252): 1.75e-97: 293: 35.06		JAG2_HUMAN (680-1031): 1.7e-13: 77.8: 16.34
+	Hs
		589611 KLK2_HUMAN (1-256): 3.23e-97: 287: 32.59		JAG2_HUMAN (680-1031): 1.7e-13: 77.8: 16.34
+	Hs
		1329638 KLK15_HUMAN (16-256): 3.77e-97: 286: 36.61		JAG2_HUMAN (680-1031): 1.7e-13: 77.8: 16.34
+	Hs
		621366 CMA1_HUMAN (18-256): 4.69e-39: 137: 33.74		FAT1_HUMAN (424-588): 1.16e-33: 144: 29.24
+	Mm
		378815 GRAB_MOUSE (24-250): 1.05e-42: 147: 33.62		NOTC1_MOUSE (150-593): 1.9e-25: 117: 25.61
+	Hs
		621387 CMA1_HUMAN (18-256): 4.69e-39: 137: 33.74		JAG2_HUMAN (680-1031): 1.7e-13: 77.8: 16.34
+	Hs
		621380 CMA1_HUMAN (18-256): 4.69e-39: 137: 33.74		SORL_HUMAN (1210-1401): 2.39e-11: 70.9: 7.18