HitPredict

Interactor 1: RAF1 (P04049)
RAF proto-oncogene serine/threonine-protein kinase (EC 2.7.11.1) (Proto-oncogene c-RAF) (cRaf) (Raf-1)
Gene: RAF1

Interactor 2: GBB1 (P62873)
Guanine nucleotide-binding protein G(I)/G(S)/G(T) subunit beta-1 (Transducin beta chain 1)
Gene: GNB1

Species: Homo sapiens

Source: biogrid

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.38	0.60	0.479

Property	Details
Experiments	36244648
Identification Methods	affinity chromatography technology
Interaction Type	physical association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0005737 - cytoplasm GO:0005829 - cytosol GO:0005886 - plasma membrane GO:0007165 - signal transduction GO:0007265 - Ras protein signal transduction
Homologous interactions	6

Homologous interactions

Color coding for hit scores

	1 648 Hs			1 340
+	Hs
		374013 RAF1_HUMAN (1-648): 0: 652: 100.00		GBB2_HUMAN (1-340): 1e-105: 314: 90.29
+	Hs
		374390 RAF1_HUMAN (1-648): 0: 652: 100.00		Q6FHM2_HUMAN (1-340): 1e-105: 314: 90.29
+	Hs
		374672 RAF1_HUMAN (1-648): 0: 652: 100.00		SNR40_HUMAN (130-340): 2.9e-59: 196: 24.30
+	Hs
		373991 RAF1_HUMAN (1-648): 0: 652: 100.00		WDR5_HUMAN (4-211): 4.16e-56: 187: 20.93
+	Hs
		412122 FYN_HUMAN (337-607): 2.33e-103: 326: 34.55		GBB1_HUMAN (1-340): 7.02e-105: 312: 100.00
+	Hs
		412300 FYN_HUMAN (337-607): 2.33e-103: 326: 34.55		SNR40_HUMAN (130-340): 2.9e-59: 196: 24.30