HitPredict

Interactor 1: RASH (P01112)
GTPase HRas (EC 3.6.5.2) (H-Ras-1) (Ha-Ras) (Transforming protein p21) (c-H-ras) (p21ras) [Cleaved into: GTPase HRas, N-terminally processed]
Gene: HRAS

Interactor 2: VAMP2 (P63027)
Vesicle-associated membrane protein 2 (VAMP-2) (Synaptobrevin-2)
Gene: VAMP2

Species: Homo sapiens

Source: biogrid

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.56	0.60	0.584

Property	Details
Experiments	30639242, 30194290
Identification Methods	proximity labelling technology
Interaction Type	physical association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0005829 - cytosol GO:0005886 - plasma membrane GO:0048471 - perinuclear region of cytoplasm
Homologous interactions	20

Homologous interactions (Top 20)

Color coding for hit scores

	1 189 Hs			1 116
+	Hs
		373850 RASN_HUMAN (1-188): 4.47e-88: 257: 85.64		VAMP7_HUMAN (3-96): 2.55e-30: 109: 31.31
+	Hs
		375308 RASK_HUMAN (1-188): 1.61e-84: 249: 86.24		VAMP7_HUMAN (3-96): 2.55e-30: 109: 31.31
+	Hs
		278465 RASN_HUMAN (1-188): 4.47e-88: 257: 85.64		VAMP4_HUMAN (18-99): 3.79e-27: 98.9: 35.37
+	Hs
		192161 RASN_HUMAN (1-188): 4.47e-88: 257: 85.64		YKT6_HUMAN (5-85): 5.35e-25: 95.1: 24.69
+	Hs
		373869 RASN_HUMAN (1-188): 4.47e-88: 257: 85.64		VAMP2_HUMAN (25-116): 5.69e-26: 95.1: 100.00
+	Hs
		373946 RASN_HUMAN (1-188): 4.47e-88: 257: 85.64		VAMP3_HUMAN (26-98): 5.64e-25: 92.4: 91.78
+	Hs
		278466 RASK_HUMAN (1-188): 1.61e-84: 249: 86.24		VAMP4_HUMAN (18-99): 3.79e-27: 98.9: 35.37
+	Hs
		374170 RASN_HUMAN (1-188): 4.47e-88: 257: 85.64		VAMP8_HUMAN (20-99): 1.87e-24: 90.8: 32.50
+	Hs
		192163 RASK_HUMAN (1-188): 1.61e-84: 249: 86.24		YKT6_HUMAN (5-85): 5.35e-25: 95.1: 24.69
+	Hs
		375379 RASK_HUMAN (1-188): 1.61e-84: 249: 86.24		VAMP2_HUMAN (25-116): 5.69e-26: 95.1: 100.00
+	Hs
		375553 RASK_HUMAN (1-188): 1.61e-84: 249: 86.24		VAMP3_HUMAN (26-98): 5.64e-25: 92.4: 91.78
+	Hs
		375898 RASK_HUMAN (1-188): 1.61e-84: 249: 86.24		VAMP8_HUMAN (20-99): 1.87e-24: 90.8: 32.50
+	Hs
		907998 RB11A_HUMAN (4-178): 6.31e-73: 220: 33.90		VAMP7_HUMAN (3-96): 2.55e-30: 109: 31.31
+	Hs
		278488 RB11A_HUMAN (4-178): 6.31e-73: 220: 33.90		VAMP4_HUMAN (18-99): 3.79e-27: 98.9: 35.37
+	Hs
		981286 RAB1A_HUMAN (4-186): 2.78e-74: 223: 31.28		VAMP3_HUMAN (26-98): 5.64e-25: 92.4: 91.78
+	Hs
		192236 RB11A_HUMAN (4-178): 6.31e-73: 220: 33.90		YKT6_HUMAN (5-85): 5.35e-25: 95.1: 24.69
+	Hs
		976192 RB11A_HUMAN (4-178): 6.31e-73: 220: 33.90		VAMP2_HUMAN (25-116): 5.69e-26: 95.1: 100.00
+	Hs
		976291 RB11A_HUMAN (4-178): 6.31e-73: 220: 33.90		VAMP3_HUMAN (26-98): 5.64e-25: 92.4: 91.78
+	Hs
		976525 RB11A_HUMAN (4-178): 6.31e-73: 220: 33.90		VAMP8_HUMAN (20-99): 1.87e-24: 90.8: 32.50
+	Hs
		91880 RB11A_HUMAN (4-178): 6.31e-73: 220: 33.90		C9JXZ5_HUMAN (46-99): 1.06e-20: 80.5: 37.04