Interactor 1: RASH (P01112)
GTPase HRas (EC 3.6.5.2) (H-Ras-1) (Ha-Ras) (Transforming protein p21) (c-H-ras) (p21ras) [Cleaved into: GTPase HRas, N-terminally processed]
Gene: HRAS

Interactor 2: RIN1 (Q13671)
Ras and Rab interactor 1 (Ras inhibitor JC99) (Ras interaction/interference protein 1)
Gene: RIN1

Species: Homo sapiens

Source: mint

Category: Small-scale

Confidence: High

Method score Annotation score Interaction score
0.96 1.00 0.983

The method score is based on:

Property Details
Experiments 28514442, 33961781, 15886098, 15031288, 7862125, 34591612, 9144171, 24441586, 10545207, 11784866, 34591642, unassigned3799
Identification Methods affinity chromatography technology, two hybrid, pull down, biochemical, coimmunoprecipitation, genetic interference, nuclear magnetic resonance, surface plasmon resonance, anti bait coimmunoprecipitation, anti tag coimmunoprecipitation
Interaction Type physical association, direct interaction, association

The annotation score is based on:

Property Details
Interacting Pfam domains RA~Ras, Ras~VPS9
Common GO terms GO:0005737 - cytoplasm
GO:0005829 - cytosol
GO:0005886 - plasma membrane
GO:0006897 - endocytosis
GO:0007165 - signal transduction
Homologous interactions 18

Homologous interactions

Color coding for hit scores

1 189
Hs

1 783
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Last updated: 11Aug2025