HitPredict

Interactor 1: RAP1B (P61224)
Ras-related protein Rap-1b (EC 3.6.5.2) (GTP-binding protein smg p21B)
Gene: RAP1B

Interactor 2: RIN1 (Q13671)
Ras and Rab interactor 1 (Ras inhibitor JC99) (Ras interaction/interference protein 1)
Gene: RIN1

Species: Homo sapiens

Source: intact

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.33	1.00	0.575

Property	Details
Experiments	unassigned3799
Identification Methods	anti tag coimmunoprecipitation
Interaction Type	association

Property	Details
Interacting Pfam domains	RA~Ras, Ras~VPS9
Common GO terms	GO:0005829 - cytosol GO:0005886 - plasma membrane
Homologous interactions	20

Homologous interactions (Top 20)

Color coding for hit scores

	1 184 Hs			1 783
+	Hs
		959439 RAP2B_HUMAN (1-184): 1.47e-65: 200: 61.41		RIN1_HUMAN (1-783): 0: 717: 100.00
+	Hs
		518598 RAP2A_HUMAN (1-166): 6.93e-61: 188: 65.66		RIN1_HUMAN (1-783): 0: 717: 100.00
+	Hs
		374583 RASH_HUMAN (1-167): 1.23e-55: 175: 57.49		RIN1_HUMAN (1-783): 0: 717: 100.00
+	Hs
		375499 RASK_HUMAN (1-167): 6.29e-55: 174: 57.49		RIN1_HUMAN (1-783): 0: 717: 100.00
+	Hs
		373918 RASN_HUMAN (1-167): 5.05e-54: 171: 56.89		RIN1_HUMAN (1-783): 0: 717: 100.00
+	Mm
		1222732 RASH_MOUSE (1-167): 1.23e-55: 175: 57.49		RIN1_MOUSE (1-783): 0: 669: 77.23
+	Hs
		374817 RASH_HUMAN (1-167): 1.23e-55: 175: 57.49		RIN2_HUMAN (41-705): 0: 570: 29.22
+	Ce
		110101 RAC1_CAEEL (1-184): 2.66e-77: 230: 27.41		G5EBS9_CAEEL (2-709): 7.24e-148: 458: 14.78
+	Hs
		976643 RB11A_HUMAN (4-178): 2.13e-69: 211: 28.98		RABX5_HUMAN (287-630): 4.47e-96: 309: 14.29
+	Hs
		958046 RAB14_HUMAN (4-178): 7.99e-69: 209: 33.52		RABX5_HUMAN (287-630): 4.47e-96: 309: 14.29
+	Hs
		375001 RASH_HUMAN (1-167): 1.23e-55: 175: 57.49		RABX5_HUMAN (287-630): 4.47e-96: 309: 14.29
+	Hs
		376072 RASK_HUMAN (1-167): 6.29e-55: 174: 57.49		RABX5_HUMAN (287-630): 4.47e-96: 309: 14.29
+	Hs
		988441 RAC1_HUMAN (1-184): 1.74e-77: 231: 27.55		TENS3_HUMAN (28-227): 1.04e-41: 167: 20.37
+	Dm
		355941 O96692_DROME (1-166): 2.57e-60: 187: 60.24		SPRI_DROME (51-350): 7.86e-55: 207: 23.63
+	Hs
		959367 RAP1B_HUMAN (1-184): 1.97e-74: 223: 100.00		RIN3_HUMAN (9-369): 1.28e-36: 150: 23.21
+	Hs
		1216704 Q5U0I6_HUMAN (4-183): 1.58e-73: 221: 31.49		RIN3_HUMAN (9-369): 1.28e-36: 150: 23.21
+	Hs
		981323 RAB1A_HUMAN (4-183): 1.58e-73: 221: 31.49		RIN3_HUMAN (9-369): 1.28e-36: 150: 23.21
+	Hs
		76307 B4DMN1_HUMAN (4-178): 6.43e-71: 216: 28.98		RIN3_HUMAN (9-369): 1.28e-36: 150: 23.21
+	Hs
		375613 RASK_HUMAN (1-167): 6.29e-55: 174: 57.49		TENS3_HUMAN (28-227): 1.04e-41: 167: 20.37
+	Ce
		110770 RAC1_CAEEL (1-184): 2.66e-77: 230: 27.41		G5ECF0_CAEEL (56-186): 2.72e-22: 105: 33.78