HitPredict

Interactor 1: RPC1 (P04051)
DNA-directed RNA polymerase III subunit RPC1 (RNA polymerase III subunit C1) (EC 2.7.7.6) (DNA-directed RNA polymerase III largest subunit) (RNA polymerase III subunit C160)
Gene: RPO31

Interactor 2: RPC2 (P22276)
DNA-directed RNA polymerase III subunit RPC2 (RNA polymerase III subunit C2) (EC 2.7.7.6) (C128) (DNA-directed RNA polymerase III 130 kDa polypeptide)
Gene: RET1

Species: Saccharomyces cerevisiae S288C

Source: mint

Category: Small-scale

Confidence: High

Method score Annotation score Interaction score
0.95 1.00 0.977

The method score is based on:

Property Details
Experiments 11805826, 16554755, 16429126, 26423792, 30593915, 29177422, 21048197, 20887893, 30192228, 37968396, 36190433, 14759368
Identification Methods tandem affinity purification, affinity chromatography technology, pull down, anti tag coimmunoprecipitation
Interaction Type physical association, direct interaction, association

The annotation score is based on:

Property Details
Interacting Pfam domains RNA_pol_Rpb1_1~RNA_pol_Rpb2_1, RNA_pol_Rpb1_1~RNA_pol_Rpb2_6, RNA_pol_Rpb1_1~RNA_pol_Rpb2_7, RNA_pol_Rpb1_2~RNA_pol_Rpb2_6, RNA_pol_Rpb1_2~RNA_pol_Rpb2_7, RNA_pol_Rpb1_3~RNA_pol_Rpb2_1, RNA_pol_Rpb1_3~RNA_pol_Rpb2_6, RNA_pol_Rpb1_4~RNA_pol_Rpb2_1, RNA_pol_Rpb1_4~RNA_pol_Rpb2_3, RNA_pol_Rpb1_4~RNA_pol_Rpb2_4, RNA_pol_Rpb1_4~RNA_pol_Rpb2_5, RNA_pol_Rpb1_4~RNA_pol_Rpb2_6, RNA_pol_Rpb1_5~RNA_pol_Rpb2_1, RNA_pol_Rpb1_5~RNA_pol_Rpb2_3, RNA_pol_Rpb1_5~RNA_pol_Rpb2_5, RNA_pol_Rpb1_5~RNA_pol_Rpb2_6, RNA_pol_Rpb1_5~RNA_pol_Rpb2_7
Common GO terms GO:0001056 - RNA polymerase III activity
GO:0003677 - DNA binding
GO:0005634 - nucleus
GO:0005654 - nucleoplasm
GO:0005666 - RNA polymerase III complex
and 5 others

more...
Homologous interactions 20

Homologous interactions (Top 20)

Color coding for hit scores

1 1460
Sc

1 1149
+ Hs
+ Hs
+ Dm
+ Bt
+ Hs
+ Hs
+ Sp
+ Sc
+ Hs
+ Hs
+ Pf
+ Hv
+ Pf
+ Hv
+ At
+ Nv
+ Ec
+ Hv
+ Hv
+ Bs

Service provided by Combinatics, Japan

Last updated: 15 Jul 2024